Crețu Bianca-Elena-Beatrice, Nita Loredana Elena, Șerban Alexandru-Mihail, Rusu Alina Gabriela, Doroftei Florica, Chiriac Aurica P
Department of Natural Polymers, Bioactive and Biocompatible Materials, Petru Poni Institute of Macromolecular Chemistry, 41 A Grigore Ghica Voda Alley, 700487 Iasi, Romania.
Nanomaterials (Basel). 2022 Jul 14;12(14):2420. doi: 10.3390/nano12142420.
Physical cryogels were obtained using the successive freeze-thaw technique of poly(vinyl alcohol) (PVA)/poly(ethylene brassylate-co-squaric acid) (PEBSA) solutions. The cryogel systems were prepared by using two different molecular weights of PVA and PEBSA with three different ratios between the ethylene brassylate (EB) and squaric acid (SA) comonomers. The presence of interactions, the thermal properties and the morphology were investigated using Fourier Transform Infrared Spectroscopy (FT-IR), thermogravimetry (TGA and DTG) and scanning electron microscopy (SEM), respectively. The influence of the composition on the degree of swelling in a physiological environment was demonstrated. The study highlighted improvements in terms of new network flexibility due to the intermolecular chains interactions brought by the introduction of PEBSA in the cryogel structure. We also concluded that the presence of PEBSA in the PVA/PEBSA cryogel network improved the loading capacity of the new system with specific hydrophobic agents, for example essential oils, which (due to their antimicrobial character) can lead to the use of new systems obtained for various applications.
通过聚（乙烯醇）（PVA）/聚（乙撑溴化物 - 共 - 方酸）（PEBSA）溶液的连续冻融技术获得物理冷冻凝胶。冷冻凝胶体系是通过使用两种不同分子量的PVA和PEBSA以及乙撑溴化物（EB）和方酸（SA）共聚单体之间的三种不同比例制备的。分别使用傅里叶变换红外光谱（FT - IR）、热重分析（TGA和DTG）和扫描电子显微镜（SEM）研究相互作用的存在、热性能和形态。证明了组成对生理环境中溶胀度的影响。该研究强调了由于在冷冻凝胶结构中引入PEBSA所带来的分子间链相互作用，新网络灵活性方面的改进。我们还得出结论，PVA/PEBSA冷冻凝胶网络中PEBSA的存在提高了新体系对特定疏水剂（例如精油）的负载能力，由于其抗菌特性，这可能导致所获得的新体系用于各种应用。
