Morgado Debora Salgado, Castro Rodolfo, Ribeiro-Alves Marcelo, Corrêa-Moreira Danielly, Castro-Alves Julio, Pereira Sandro Antonio, Menezes Rodrigo Caldas, Oliveira Manoel Marques Evangelista
Laboratory of Clinical Research on Dermatozoonoses in Domestic Animals, Evandro Chagas National Institute of Infectious Diseases, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.
Department of Education, Evandro Chagas National Institute of Infectious Diseases, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.
Curr Res Microb Sci. 2022 May 19;3:100140. doi: 10.1016/j.crmicr.2022.100140. eCollection 2022.
Sporotrichosis is a subcutaneous mycosis caused by thermodimorphic fungi of the genus Sporothrix. The phenotypic and genotypic differences of the isolates within the genus Sporothrix have been associated with their geographic distribution, virulence capacity, or clinical manifestation of sporotrichosis. Therefore, it is crucial to identify the causative agent of sporotrichosis. However, there are few case reports and studies in animals compared to those in humans, despite the substantial increase in the number of cases of sporotrichosis by zoonotic transmission, especially in endemic areas. Considering the epidemiological importance, taxonomic evolution and worldwide distribution of these fungi in the last decade, there is interest in identifying the species of the genus Sporothrix in different regions of the world. This study aimed to analyze the geographic distribution of animal sporotrichosis in the world, caused by pathogenic species identified by use of molecular tools. This systematic review of articles from 2007 to 2021 analyzed the geographic distribution of species that cause sporotrichosis in cats, dogs and other animals. It demonstrated that the most identified species were S. brasiliensis, isolated from cats in Brazil and S. schenckii isolated from cats in Malaysia. We show the lack of studies in global areas and reinforce the need to use molecular tools to identify and monitor potential pathogens.
孢子丝菌病是一种由孢子丝菌属的双相真菌引起的皮下真菌病。孢子丝菌属内分离株的表型和基因型差异与其地理分布、毒力或孢子丝菌病的临床表现有关。因此，鉴定孢子丝菌病的病原体至关重要。然而，尽管人畜共患传播导致的孢子丝菌病病例数量大幅增加，尤其是在流行地区，但与人类病例相比，动物病例报告和研究较少。考虑到这些真菌在过去十年中的流行病学重要性、分类学演变和全球分布情况，人们对鉴定世界不同地区的孢子丝菌属物种很感兴趣。本研究旨在分析世界范围内由使用分子工具鉴定出的致病物种引起的动物孢子丝菌病的地理分布。这项对2007年至2021年文章的系统综述分析了导致猫、狗和其他动物孢子丝菌病的物种的地理分布。结果表明，最常鉴定出的物种是从巴西猫身上分离出的巴西孢子丝菌和从马来西亚猫身上分离出的申克孢子丝菌。我们指出全球范围内缺乏相关研究，并强调需要使用分子工具来鉴定和监测潜在病原体。
