College of Life Science and Technology, Harbin Normal University, Harbin 150025, China.
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China.
Molecules. 2022 Aug 5;27(15):4991. doi: 10.3390/molecules27154991.
Nakai is a Chinese traditional medicinal fern plant for heat-clearing and detoxifying, promoting blood circulation and dissipating blood stasis. Previous researches showed that many factors could influence the components of medicinal plants, and the plant part is one of the main factors. So far, only the underground part of , called "Mianma Guanzhong", has been widely sold in the market. However, the above-ground part was usually at low utilization, resulting in a waste of medicinal resources. In order to further develop and utilize the medicinal resources of , the constituents, total flavonoid contents and antioxidant activity of the above-ground and underground parts of were tentatively analyzed and compared based on HS-SPME-GC-MS and UPLC/Q-TOF-MS. The results showed that (1) the volatile components were mainly focused in the above-ground part of , including 3-carene, isoledene, ionene, 4-amino-1-naphthol and furfural. (2) Nonvolatile components of the underground part of contained phenolic acid, flavonoids, phloroglucinol and less fatty acid. (3) The common compounds of the above-ground and underground parts of were phenolic acid and flavaspidic acid AB. (4) Antioxidant activity of the underground part was stronger than that of the above-ground part of . In conclusion, both the above-ground and underground parts of are important medicinal resources worthy of further development.
Nakai 是一种用于清热、解毒、活血、化瘀的中国传统药用蕨类植物。先前的研究表明，许多因素会影响药用植物的成分，而植物部位是主要因素之一。迄今为止，只有地下部分的“绵马贯众”在市场上广泛销售。然而，地上部分通常利用率较低，造成药用资源浪费。为了进一步开发和利用绵马贯众的药用资源，基于 HS-SPME-GC-MS 和 UPLC/Q-TOF-MS，对绵马贯众地上部分和地下部分的成分、总黄酮含量和抗氧化活性进行了初步分析和比较。结果表明：（1）挥发性成分主要集中在绵马贯众的地上部分，包括 3-蒈烯、异戊二烯、依兰烯、4-氨基-1-萘酚和糠醛。（2）地下部分的非挥发性成分含有酚酸、类黄酮、间苯三酚和较少的脂肪酸。（3）绵马贯众地上部分和地下部分的共同化合物为酚酸和 flavaspidic acid AB。（4）地下部分的抗氧化活性强于地上部分。总之，绵马贯众的地上部分和地下部分都是值得进一步开发的重要药用资源。
