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全球基因组编辑:政策和认知的最新进展。

Genome editing around the globe: An update on policies and perceptions.

机构信息

Julius Kuehn Institute (JKI) - Federal Research Centre for Cultivated Plants, Institute for Biosafety in Plant Biotechnology, Quedlinburg, Saxony-Anhalt, Germany.

出版信息

Plant Physiol. 2022 Oct 27;190(3):1579-1587. doi: 10.1093/plphys/kiac359.

Abstract

A decade ago, the CRISPR/Cas system has been adapted for genome editing. Since then, hundreds of organisms have been altered using genome editing and discussions were raised on the regulatory status of genome edited organisms esp. crops. To date, many countries have made decisions on the regulatory status of products of genome editing, by exempting some kinds of edits from the classical GMO regulation. However, the guidance differs between countries even in the same region. Several countries are still debating the issue or are in the progress of updating guidance and regulatory systems to cover products of genome editing. The current global situation of different regulatory systems is putting a harmonized framework on genome-edited crops in the far future. In this update, we summarize the current developments in the field of regulation concerning edited crops and present a short insight into perception of genome editing in the society.

摘要

十年前,CRISPR/Cas 系统被用于基因组编辑。从那时起,已经有数百种生物体使用基因组编辑进行了修改,并且对基因组编辑生物体特别是作物的监管状况进行了讨论。迄今为止,许多国家已经对基因组编辑产品的监管状况做出了决定,豁免了某些类型的编辑受经典 GMO 监管。然而,即使在同一地区,各国的指导方针也存在差异。一些国家仍在讨论这个问题,或正在更新指导方针和监管体系以涵盖基因组编辑产品。当前不同监管体系的全球情况使得在遥远的未来建立一个协调的框架来监管经基因编辑的作物变得更加困难。在本次更新中,我们总结了编辑作物领域监管的最新进展,并简要介绍了社会对基因组编辑的看法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d89/9614466/9f3dabc96a1e/kiac359f1.jpg

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