通过病毒假型转移至大鼠细胞的单个小鼠VL30元件保留了它们对蛋白激酶C激活剂的反应性。

Individual mouse VL30 elements transferred to rat cells by viral pseudotypes retain their responsiveness to activators of protein kinase C.

作者信息

Rodland K D, Brown A M, Magun B E

出版信息

Mol Cell Biol. 1987 Jun;7(6):2296-8. doi: 10.1128/mcb.7.6.2296-2298.1987.

DOI:10.1128/mcb.7.6.2296-2298.1987

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC365355/

Abstract

By exploiting the retroviral characteristics of mouse VL30 elements, we transferred individual copies of VL30 to Rat-1 cells by infection. Analysis of clonal isolates containing single VL30 elements integrated into the Rat-1 genome indicates that responsiveness to activators of protein kinase C is an inherent property of at least some of the VL30 sequences.

摘要

通过利用小鼠VL30元件的逆转录病毒特性，我们通过感染将单个VL30拷贝转移到Rat-1细胞中。对含有整合到Rat-1基因组中的单个VL30元件的克隆分离株的分析表明，对蛋白激酶C激活剂的反应性是至少一些VL30序列的固有特性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae8a/365355/233bc61c2cfa/molcellb00078-0269-a.jpg

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