Department of Oral Implantology, Hospital of Stomatology, Jilin University, Changchun, 130021, China.
Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Hospital of Stomatology, Jilin University, Changchun, 130021, China.
Biomater Sci. 2022 Oct 11;10(20):5786-5808. doi: 10.1039/d2bm00969b.
The exploration of nanomaterials is beneficial for the development of nanomedicine and human medical treatment. Metal-phenolic networks (MPNs) have been introduced as a nanoplatform for versatile functional hybrid nanomaterials and have attracted extensive attention due to their simple preparation, excellent properties and promising medical application prospects. This review presents an overview of recent synthesis methods for MPNs, their unique biomedical properties and the research progress in their application in disease detection and treatment. First, the synthesis methods of MPNs are summarised, and then the advantages and applicability of each assembly method are emphasised. The various functions exhibited by MPNs in biomedical applications are then introduced. Finally, the latest research progress in MPN-based nanoplatforms in the biomedical field is discussed, and their future research and application are investigated.
纳米材料的探索有利于纳米医学和人类医疗的发展。金属-酚网络（MPN）已被引入作为多功能功能杂化纳米材料的纳米平台，由于其简单的制备、优异的性能和有前途的医学应用前景而受到广泛关注。本文综述了 MPN 的最新合成方法、它们独特的生物医学特性以及在疾病检测和治疗中的应用研究进展。首先总结了 MPN 的合成方法，然后强调了每种组装方法的优点和适用性。然后介绍了 MPN 在生物医学应用中表现出的各种功能。最后，讨论了基于 MPN 的纳米平台在生物医学领域的最新研究进展，并探讨了它们的未来研究和应用。
