Binaymotlagh Roya, Chronopoulou Laura, Haghighi Farid Hajareh, Fratoddi Ilaria, Palocci Cleofe
Department of Chemistry, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
Research Center for Applied Sciences to the Safeguard of Environment and Cultural Heritage (CIABC), Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
Materials (Basel). 2022 Aug 25;15(17):5871. doi: 10.3390/ma15175871.
Peptide-based hydrogels have attracted increasing attention for biological applications and diagnostic research due to their impressive features including biocompatibility and biodegradability, injectability, mechanical stability, high water absorption capacity, and tissue-like elasticity. The aim of this review will be to present an updated report on the advancement of peptide-based hydrogels research activity in recent years in the field of anticancer drug delivery, antimicrobial and wound healing materials, 3D bioprinting and tissue engineering, and vaccines. Additionally, the biosensing applications of this key group of hydrogels will be discussed mainly focusing the attention on cancer detection.
基于肽的水凝胶因其具有生物相容性、可生物降解性、可注射性、机械稳定性、高吸水能力和类似组织的弹性等令人印象深刻的特性，在生物应用和诊断研究中受到越来越多的关注。本综述的目的是提供一份最新报告，介绍近年来基于肽的水凝胶在抗癌药物递送、抗菌和伤口愈合材料、3D生物打印和组织工程以及疫苗等领域的研究进展。此外，还将讨论这类关键水凝胶的生物传感应用，主要聚焦于癌症检测。
