The Department of Urology, West China Hospital, Department of Sichuan University, West China Hospital of Sichuan University, No. 37 Guoxue Xiang, Chengdu, 610041, Sichuan, China.
The Department of Neurology, West China Hospital, Department of Sichuan University, West China Hospital of Sichuan University, No. 37 Guoxue Xiang, Chengdu, 610041, Sichuan, China.
BMC Public Health. 2022 Sep 20;22(1):1787. doi: 10.1186/s12889-022-14187-5.
Growing number of studies have evidently shown that sleep disorders are associated with the recently increased risk of various diseases in general human population. However, the relationship between sleep quality and urolithiasis condition in humans is still unclear. The present study explored the relationship between quality of sleep and urolithiasis in Chinese population of population, western China and hence investigated the effects of sleep quality on urolithiasis disease.
A cross-sectional analysis was performed using data from the West China Natural Population Cohort Study (WCNPCS). The data was collected between May 2019 and June 2021. This study evaluated the association between the sleep quality and urolithiasis. The sleep quality was assessed using the Chinese version of the Pittsburgh Sleep Quality Index (PSQI) whereas urolithiasis, as the outcome was a binary variable. Multivariable logistic regression models that adjust the sociodemographic characteristics and health-related factors were used to assess the association between sleep quality and urolithiasis. Interaction was tested in prespecified subgroup of interest.
After adjusting a series of confounding variables, the Pittsburgh Sleep Quality Index scores were found to have a significant positive correlation with the prevalence of urolithiasis (OR: 1.178; 95% CI = 1.083-1.282; p < 0.001). The risk of urolithiasis was significantly increased with an elevation of the component Pittsburgh Sleep Quality Index score in sleep latency, sleep duration, habitual sleep efficiency, and daytime dysfunction.
It was evident that there is an association between sleep quality and prevalence of renal stones in natural population in western China regions. Poor sleep quality is related to urolithiasis. The findings of the current study hence highlighted the need for future public health guidelines to develop detailed strategies for improving sleep quality.
越来越多的研究表明，睡眠障碍与一般人群中各种疾病的风险增加有关。然而，睡眠质量与人类尿石症之间的关系尚不清楚。本研究探讨了中国人群中睡眠质量与尿石症之间的关系，因此研究了睡眠质量对尿石症的影响。
采用中国西部自然人群队列研究（WCNPCS）的数据进行横断面分析。数据收集于 2019 年 5 月至 2021 年 6 月。本研究评估了睡眠质量与尿石症之间的关系。睡眠质量采用匹兹堡睡眠质量指数（PSQI）的中文版进行评估，而尿石症作为结果是一个二分变量。使用多变量逻辑回归模型调整社会人口统计学特征和健康相关因素来评估睡眠质量与尿石症之间的关系。在预先指定的感兴趣的亚组中测试了交互作用。
在调整了一系列混杂变量后，匹兹堡睡眠质量指数评分与尿石症的患病率呈显著正相关（OR：1.178；95%CI=1.083-1.282；p<0.001）。随着睡眠潜伏期、睡眠时间、习惯性睡眠效率和日间功能障碍的匹兹堡睡眠质量指数评分升高，尿石症的风险显著增加。
中国西部自然人群中睡眠质量与肾结石患病率之间存在关联。睡眠质量差与尿石症有关。本研究的结果强调了未来公共卫生指南制定详细改善睡眠质量策略的必要性。
