Department of Green Bio Engineering, Korea National University of Transportation, Chungju 27469, Korea.
Department of Bioengineering, College of Engineering, Hanyang University, Seoul 04763, Korea.
Biosensors (Basel). 2022 Sep 6;12(9):731. doi: 10.3390/bios12090731.
After the COVID-19 pandemic, the development of an accurate diagnosis and monitoring of diseases became a more important issue. In order to fabricate high-performance and sensitive biosensors, many researchers and scientists have used many kinds of nanomaterials such as metal nanoparticles (NPs), metal oxide NPs, quantum dots (QDs), and carbon nanomaterials including graphene and carbon nanotubes (CNTs). Among them, CNTs have been considered important biosensing channel candidates due to their excellent physical properties such as high electrical conductivity, strong mechanical properties, plasmonic properties, and so on. Thus, in this review, CNT-based biosensing systems are introduced and various sensing approaches such as electrochemical, optical, and electrical methods are reported. Moreover, such biosensing platforms showed excellent sensitivity and high selectivity against not only viruses but also virus DNA structures. So, based on the amazing potential of CNTs-based biosensing systems, healthcare and public health can be significantly improved.
在 COVID-19 大流行之后,准确诊断和监测疾病的发展成为一个更加重要的问题。为了制造高性能和高灵敏度的生物传感器,许多研究人员和科学家使用了许多种纳米材料,如金属纳米粒子(NPs)、金属氧化物 NPs、量子点(QDs)和碳纳米材料,包括石墨烯和碳纳米管(CNTs)。其中,由于 CNTs 具有高导电性、强机械性能、等离子体性能等优异的物理性质,因此被认为是重要的生物传感通道候选材料。因此,在本综述中,介绍了基于 CNT 的生物传感系统,并报告了各种传感方法,如电化学、光学和电学方法。此外,这种生物传感平台对病毒和病毒 DNA 结构都表现出了优异的灵敏度和高选择性。因此,基于 CNT 基生物传感系统的惊人潜力,可以显著改善医疗保健和公共卫生。