Shaheen Nour, Diab Rehab Adel, Meshref Mostafa, Shaheen Ahmed, Ramadan Abdelraouf, Shoib Sheikh
Alexandria Faculty of Medicine, Alexandria, Egypt.
Faculty of Medicine Al-Azhar University, Cairo, Egypt.
Ann Med Surg (Lond). 2022 Aug 19;81:104396. doi: 10.1016/j.amsu.2022.104396. eCollection 2022 Sep.
The Monkeypox virus (MPXV) is a double-stranded DNA virus related to the orthopoxvirus genus in the family of poxviridae. MPXV is endemic in central and Western African countries. There have been several outbreaks of MPXV in non-endemic countries since it was discovered in 1958 in lab monkeys. The current spread of MPXV is different from previous outbreaks, raising concerns about its potential to cause pandemics around the world. In order to reduce the spread of the disease, several countries imposed different preventive measures. The MPXV virus is believed to be transmitted either through wild animals, such as rodents or through infected individuals. Every year, Africa experiences a few thousand cases, mostly in the west and central regions. The number of cases outside Africa has previously been limited to a handful associated with travel to Africa or with the importation of infected animals. In this narrative review, we will discuss the clinical diagnosis, transmission, distribution, treatment, and prevention of the recent monkeypox outbreak around the world.
猴痘病毒（MPXV）是一种双链DNA病毒，与痘病毒科正痘病毒属相关。MPXV在中非和西非国家呈地方性流行。自1958年在实验室猴子中发现以来，非流行国家已发生多次MPXV疫情。当前MPXV的传播与以往疫情不同，引发了对其在全球引发大流行可能性的担忧。为减少疾病传播，多个国家采取了不同的预防措施。据信MPXV病毒通过野生动物（如啮齿动物）或感染者传播。非洲每年有数千例病例，主要集中在西部和中部地区。此前非洲以外的病例数量仅限于少数与前往非洲旅行或进口受感染动物相关的病例。在这篇叙述性综述中，我们将讨论近期全球猴痘疫情的临床诊断、传播、分布、治疗和预防。
