自发的香烟品牌转换：对尼古丁和一氧化碳暴露的影响。
Spontaneous cigarette brand switching: consequences for nicotine and carbon monoxide exposure.
作者信息
Lynch C J, Benowitz N L
出版信息
Am J Public Health. 1987 Sep;77(9):1191-4. doi: 10.2105/ajph.77.9.1191.
Abstract
A group of smokers who had participated in smoking-related studies three to six years earlier were re-studied to assess changes in their smoking practices. Individuals who smoked the same brands of cigarettes showed no change in plasma cotinine (reflecting exposure to nicotine) or expired carbon monoxide (CO) concentration. Those who switched to cigarettes of lower nicotine yield (average decrease 38 per cent) showed reduced plasma cotinine concentrations, due primarily to smoking fewer cigarettes per day. The intake of nicotine per cigarette was not different. Subjects who smoked cigarettes of higher yield (102 per cent increase) had higher cotinine and CO levels, due to greater intake per cigarette.
摘要
一组在三到六年前参与过吸烟相关研究的吸烟者接受了重新研究，以评估他们吸烟习惯的变化。吸同一品牌香烟的个体，其血浆可替宁（反映尼古丁暴露情况）或呼出一氧化碳（CO）浓度没有变化。那些转而吸尼古丁含量较低香烟（平均降低38%）的人，血浆可替宁浓度降低，主要原因是每天吸烟量减少。每支香烟的尼古丁摄入量没有差异。吸尼古丁含量较高香烟（增加102%）的受试者，由于每支香烟的摄入量更大，其可替宁和CO水平更高。
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本文引用的文献
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Clin Pharmacol Ther. 1980 May;27(5):652-8. doi: 10.1038/clpt.1980.92.
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Circadian blood nicotine concentrations during cigarette smoking.吸烟期间的昼夜血尼古丁浓度。
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Low nicotine cigarettes: cigarette consumption and breath carbon monoxide after one year.低尼古丁香烟：一年后的香烟消费量与呼出气一氧化碳含量
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Addict Behav. 1983;8(1):59-66. doi: 10.1016/0306-4603(83)90057-6.
5
Smokers of low-yield cigarettes do not consume less nicotine.低焦油香烟的吸烟者摄入的尼古丁并不少。
N Engl J Med. 1983 Jul 21;309(3):139-42. doi: 10.1056/NEJM198307213090303.
6
Cigarette smoking: carboxyhemoglobin, plasma nicotine, cotinine and thiocyanate vs self-reported smoking data and cardiovascular disease.吸烟：碳氧血红蛋白、血浆尼古丁、可替宁和硫氰酸盐与自我报告的吸烟数据及心血管疾病的关系
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