间歇性禁食 5:2 对雅加达肥胖员工身体成分和营养摄入的影响：一项随机临床试验。
Effect of intermittent fasting 5:2 on body composition and nutritional intake among employees with obesity in Jakarta: a randomized clinical trial.
机构信息
Departement of Nutrition, Faculty of Medicine, Universitas Indonesia - Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia.
出版信息
BMC Res Notes. 2022 Oct 12;15(1):323. doi: 10.1186/s13104-022-06209-7.
Abstract
OBJECTIVE
This study aimed to determine the effect of intermittent fasting 5:2 on body composition in employees with obesity in Jakarta.
RESULTS
Fifty participants were included; 25 were allocated to the fasting group and 25 to the control group. There was no significant change in fat mass, fat-free mass, skeletal muscle, and BMI (p > 0.05). Significant in-group changes were observed in body weight (p = 0.023) and BMI (p = 0.018) in the fasting group. Dietary intake was similar before and during the intervention. The reduction in macronutrient intake resulted in a statistically significant difference in carbohydrate, protein, and fat intake in the two groups (p < 0.05). Intermittent fasting 5:2 results in weight loss but does not affect fat mass and fat-free mass reductions. None of the between-group differences were clinically relevant.
TRIAL REGISTRATION
ClinicalTrials.gov with ID: NCT04319133 registered on 24 March 2020.
摘要
目的
本研究旨在确定间歇性禁食 5:2 对雅加达肥胖员工身体成分的影响。
结果
共纳入 50 名参与者，其中 25 名被分配到禁食组，25 名被分配到对照组。脂肪量、去脂体重、骨骼肌和 BMI 均无显著变化（p＞0.05）。禁食组的体重（p=0.023）和 BMI（p=0.018）有显著的组内变化。干预前后的膳食摄入量相似。宏量营养素摄入量的减少导致两组间碳水化合物、蛋白质和脂肪摄入量有统计学显著差异（p＜0.05）。间歇性禁食 5:2 可导致体重减轻，但对脂肪量和去脂体重的减少没有影响。组间差异均无临床意义。
试验注册
ClinicalTrials.gov 注册号：NCT04319133，于 2020 年 3 月 24 日注册。
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