Falus A, Merétey K, Böhm U, Bozsóky S
Experientia. 1979 Mar 15;35(3):413-4. doi: 10.1007/BF01964384.
Mild acidic treatment increases the rheumatoid factor titre of some sera and synovial fluids (SF) in rheumatoid arthritis (RA), juvenile RA (JRA) and most frequently in rheumatoid vasculitis. This unmasking of 'hidden' RF in serum and SF samples correlated with the RF-immune complexes (RF-IC) and complexed C4 present in the 3% polyethylene glycol (PEG) precipitates, indicating that by means of 'hidden' RF measurements RF-ICs are possibly detected. This method seems to provide a diagnostic tool for detecting RF-ICs in RA and other related diseases.
轻度酸性处理会使类风湿关节炎(RA)、青少年类风湿关节炎(JRA)以及最常见于类风湿性血管炎患者的部分血清和滑液(SF)中的类风湿因子滴度升高。血清和SF样本中这种“隐藏”类风湿因子的显现与3%聚乙二醇(PEG)沉淀物中存在的类风湿因子免疫复合物(RF-IC)和复合C4相关,这表明通过测量“隐藏”类风湿因子可能检测到RF-IC。该方法似乎为检测RA及其他相关疾病中的RF-IC提供了一种诊断工具。