Department of Environmental and Health Research, The Custodian of the Two Holy Mosques Institute for Hajj and Umrah Research, Umm Al-Qura University, Makkah, Saudi Arabia.
Department of Mechanical Engineering, College of Engineering and Islamic Architecture, Umm Al-Qura University, Makkah, 24372, Saudi Arabia.
Sci Rep. 2022 Nov 4;12(1):18739. doi: 10.1038/s41598-022-23615-w.
To control infectious diseases, various applications of nanotechnology have been used to enhance the self-cleaning and antibacterial properties of materials. This study aimed to evaluate the antibacterial properties of face masks coated with TiO2 nanoparticles. The antibacterial efficacies of cloth face masks coated with TiO2 were measured by inoculating them in bacterial suspensions (10 CFUs from both E. coli and S. aureus). The results showed that TiO2 nanoparticle solutions (at 2%) reduced the starting inoculum of 10 CFUs (5 log cfu/cm) of E. coli and S. aureus to 1.3 and 1.68 log, respectively, with antibacterial activities of 3.7 and 3.34 log, respectively. Furthermore, at a 1% concentration, the antibacterial activities against E. coli and S. aureus were 2.1 and 2.01 log, respectively, while at a low concentration (0.5%), the antibacterial activities against E. coli and S. aureus were 1.8 and 1.72 log, respectively. The CFUs in all the experimental groups were significantly lower than those in the control group (saline). In conclusion, TiO2 nanoparticle solutions with a high concentration (2%) demonstrated a strong antibacterial effect on E. coli and S. aureus, and the difference was statistically significant, while a significant antibacterial activity was demonstrated with lower concentration (0.5% and 1%) nanoparticle solutions of TiO2 after 18 h. There was a statistically significant difference regarding colony reduction between E. coli and S. aureus even at 3 h. The antibacterial activities of TiO2 in face masks could be promising for reducing the risk of bacterial infections.
为了控制传染病,已经应用了各种纳米技术应用来增强材料的自清洁和抗菌性能。本研究旨在评估涂覆有 TiO2 纳米粒子的口罩的抗菌性能。通过将涂覆有 TiO2 的布制口罩接种在细菌悬浮液中(大肠杆菌和金黄色葡萄球菌各 10 CFU)来测量其抗菌功效。结果表明,TiO2 纳米粒子溶液(2%)将起始接种量为 10 CFU(大肠杆菌和金黄色葡萄球菌各 5 log cfu/cm)减少到分别为 1.3 和 1.68 log,抗菌活性分别为 3.7 和 3.34 log。此外,在 1%浓度下,对大肠杆菌和金黄色葡萄球菌的抗菌活性分别为 2.1 和 2.01 log,而在低浓度(0.5%)下,对大肠杆菌和金黄色葡萄球菌的抗菌活性分别为 1.8 和 1.72 log。所有实验组的 CFU 均明显低于对照组(生理盐水)。总之,高浓度(2%)的 TiO2 纳米粒子溶液对大肠杆菌和金黄色葡萄球菌表现出强烈的抗菌作用,差异具有统计学意义,而在 18 小时后,浓度较低(0.5%和 1%)的 TiO2 纳米粒子溶液也表现出显著的抗菌活性。即使在 3 小时时,大肠杆菌和金黄色葡萄球菌的菌落减少率也存在统计学差异。口罩中 TiO2 的抗菌活性有望降低细菌感染的风险。