Nosrati-Oskouie Mohammad, Aghili-Moghaddam Nazanin Sadat, Tavakoli-Rouzbehani Omid Mohammad, Jamialahmadi Tannaz, Johnston Thomas P, Sahebkar Amirhossein
Department of Clinical Nutrition and Dietetics, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute Shahid Beheshti University of Medical Sciences Tehran Iran.
Nutrition and Endocrine Research Center, Research Institute for Endocrine Sciences Shahid Beheshti University of Medical Sciences Tehran Iran.
Food Sci Nutr. 2022 Jul 18;10(11):3531-3543. doi: 10.1002/fsn3.2983. eCollection 2022 Nov.
Curcumin, as the main natural compound in the turmeric plant (), is a yellowish polyphenol that has been used traditionally in Asian countries as a medicinal herb for various types of disease and pathological conditions caused by inflammation and oxidative stress. In the present review, we conducted a comprehensive literature search for evidence that shows the effect of curcumin on factors influencing exercise performance, including muscle damage, muscle soreness, inflammation, and oxidative stress. During exercise, reactive oxygen species and inflammation are increased. Thus, if there is no balance between endogenous and exogenous antioxidants and increases in oxidative stress and inflammation, which is important for maintaining redox homeostasis in skeletal muscle, it can lead to muscle soreness and muscle damage and ultimately result in reduced exercise performance. Due to the anti-oxidant and anti-inflammatory properties of curcumin, it can increase exercise performance and decrease exercise-induced muscle soreness and muscle damage. It appears that curcumin supplementation can have positive effects on exercise performance and recovery, muscle damage and pain, inflammation, and oxidative stress. However, there is still a need to precisely evaluate factors to more accurately assess/quantify the beneficial therapeutic effects of curcumin with regard to enhancing exercise performance and recovery.
姜黄素作为姜黄植物中的主要天然化合物,是一种淡黄色的多酚类物质,在亚洲国家传统上被用作药草,用于治疗由炎症和氧化应激引起的各种疾病和病理状况。在本综述中,我们进行了全面的文献检索,以寻找表明姜黄素对影响运动表现的因素(包括肌肉损伤、肌肉酸痛、炎症和氧化应激)有作用的证据。运动期间,活性氧和炎症会增加。因此,如果内源性和外源性抗氧化剂之间没有平衡,且氧化应激和炎症增加(这对维持骨骼肌的氧化还原稳态很重要),就会导致肌肉酸痛和肌肉损伤,最终导致运动表现下降。由于姜黄素具有抗氧化和抗炎特性,它可以提高运动表现,减轻运动引起的肌肉酸痛和肌肉损伤。姜黄素补充剂似乎对运动表现和恢复、肌肉损伤和疼痛、炎症以及氧化应激都有积极作用。然而,仍需要精确评估相关因素,以便更准确地评估/量化姜黄素在提高运动表现和恢复方面的有益治疗效果。