Department of Computer Science and Engineering, Northwest Normal University, Lanzhou, China.
BMC Bioinformatics. 2022 Dec 6;23(1):523. doi: 10.1186/s12859-022-05058-2.
Glaucoma can cause irreversible blindness to people's eyesight. Since there are no symptoms in its early stage, it is particularly important to accurately segment the optic disc (OD) and optic cup (OC) from fundus medical images for the screening and prevention of glaucoma. In recent years, the mainstream method of OD and OC segmentation is convolution neural network (CNN). However, most existing CNN methods segment OD and OC separately and ignore the a priori information that OC is always contained inside the OD region, which makes the segmentation accuracy of most methods not high enough.
This paper proposes a new encoder-decoder segmentation structure, called RSAP-Net, for joint segmentation of OD and OC. We first designed an efficient U-shaped segmentation network as the backbone. Considering the spatial overlap relationship between OD and OC, a new Residual spatial attention path is proposed to connect the encoder-decoder to retain more characteristic information. In order to further improve the segmentation performance, a pre-processing method called MSRCR-PT (Multi-Scale Retinex Colour Recovery and Polar Transformation) has been devised. It incorporates a multi-scale Retinex colour recovery algorithm and a polar coordinate transformation, which can help RSAP-Net to produce more refined boundaries of the optic disc and the optic cup.
The experimental results show that our method achieves excellent segmentation performance on the Drishti-GS1 standard dataset. In the OD and OC segmentation effects, the F1 scores are 0.9752 and 0.9012, respectively. The BLE are 6.33 pixels and 11.97 pixels, respectively.
This paper presents a new framework for the joint segmentation of optic discs and optic cups, called RSAP-Net. The framework mainly consists of a U-shaped segmentation skeleton and a residual space attention path module. The design of a pre-processing method called MSRCR-PT for the OD/OC segmentation task can improve segmentation performance. The method was evaluated on the publicly available Drishti-GS1 standard dataset and proved to be effective.
青光眼可导致人们的视力不可逆转地失明。由于其早期阶段没有症状,因此从眼底医学图像中准确地分割视盘(OD)和视杯(OC)对于青光眼的筛查和预防尤为重要。近年来,OD 和 OC 分割的主流方法是卷积神经网络(CNN)。然而,大多数现有的 CNN 方法分别分割 OD 和 OC,忽略了 OC 始终包含在 OD 区域内的先验信息,这使得大多数方法的分割精度不够高。
本文提出了一种新的用于 OD 和 OC 联合分割的编码器-解码器分割结构,称为 RSAP-Net。我们首先设计了一个高效的 U 形分割网络作为骨干。考虑到 OD 和 OC 之间的空间重叠关系,提出了一种新的残差空间注意路径来连接编码器-解码器,以保留更多的特征信息。为了进一步提高分割性能,设计了一种称为 MSRCR-PT(多尺度视网膜色彩恢复和极坐标变换)的预处理方法。它结合了多尺度视网膜色彩恢复算法和极坐标变换,可以帮助 RSAP-Net 生成更精细的视盘和视杯边界。
实验结果表明,我们的方法在 Drishti-GS1 标准数据集上取得了优异的分割性能。在 OD 和 OC 分割效果方面,F1 分数分别为 0.9752 和 0.9012,BLE 分别为 6.33 像素和 11.97 像素。
本文提出了一种新的用于视盘和视杯联合分割的框架,称为 RSAP-Net。该框架主要由 U 形分割骨架和残差空间注意路径模块组成。用于 OD/OC 分割任务的预处理方法 MSRCR-PT 的设计可以提高分割性能。该方法在公开的 Drishti-GS1 标准数据集上进行了评估,证明是有效的。