Unidad de Investigación de Enfermedades Metabólicas, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City 14080, Mexico.
The Institute for Obesity Research, Tecnologico de Monterrey, Mexico City 64700, Mexico.
Int J Environ Res Public Health. 2023 Jan 16;20(2):1608. doi: 10.3390/ijerph20021608.
Phase angle (PhA) has been used as mortality prognostic, but there are no studies about its possible use as a screening tool. Therefore, an assessment of the possible utility of PhA in clinical practice is required. The aim of this systematic review was to explore all recent available evidence of PhA, and its possible utility as a screening tool in clinical practice in subjects with chronic metabolic diseases.
This systematic review was performed and written as stated in the PRISMA 2020 guidelines. The search was conducted in PubMed, ScienceDirect and SciElo. In order to be considered eligible, within the entire search, only articles involving PhA and their utility in metabolic diseases were included.
PhA was associated with hyperuricemia and vitamin D deficiency in obese subjects, and decreased cardiovascular risk and malnutrition in hospitalized patients.
PhA may be a potential screening tool in clinical practice to evaluate different biomarkers, cardiovascular risk, and nutritional diagnosis in metabolic diseases in adults.
相位角（PhA）已被用作预测死亡率的指标，但尚无关于其用作筛查工具的可能性的研究。因此，需要评估 PhA 在临床实践中的可能用途。本系统评价的目的是探讨 PhA 的所有最新可用证据，以及其在患有慢性代谢性疾病的患者中作为临床实践筛查工具的可能用途。
本系统评价按照 PRISMA 2020 指南进行并编写。在 PubMed、ScienceDirect 和 SciElo 中进行了搜索。为了符合入选标准，在整个搜索范围内，仅纳入了涉及 PhA 及其在代谢性疾病中的应用的文章。
PhA 与肥胖人群中的高尿酸血症和维生素 D 缺乏症相关，与住院患者的心血管风险降低和营养不良相关。
PhA 可能是临床实践中评估代谢性疾病中不同生物标志物、心血管风险和营养诊断的潜在筛查工具。
