Department of Mechanical Engineering, Graphic Era Deemed to be University, Dehradun 248002, Uttarakhand, India.
Mechanical Engineering Department, SOET, HNB Garhwal University, Srinagar 246174, Uttarakhand, India.
Molecules. 2023 Jan 4;28(2):485. doi: 10.3390/molecules28020485.
In the present scenario, the research is now being focused on the naturally occurring polymers that can gradually replace the existing synthetic polymers for the development of bio composites having applications in medical surgeries and human implants. With promising mechanical properties and bio compatibility with human tissues, poly lactic acid (PLA) is now being viewed as a future bio material. In order to examine the applicability of PLA in human implants, the current article sheds light on the synthesis of PLA and its various copolymers used to alter its physical and mechanical properties. In the latter half, various processes used for the fabrication of biomaterials are discussed in detail. Finally, biomaterials that are currently in use in the field of biomedical (Scaffolding, drug delivery, tissue engineering, medical implants, derma, cosmetics, medical surgeries, and human implants) are represented with respective advantages in the sphere of biomaterials.
在当前的情况下，研究现在集中在天然存在的聚合物上，这些聚合物可以逐渐取代现有的合成聚合物，用于开发具有医学手术和人体植入应用的生物复合材料。聚乳酸 (PLA) 具有有前景的机械性能和与人组织的生物相容性，现在被视为未来的生物材料。为了研究 PLA 在人体植入物中的适用性，本文介绍了 PLA 的合成及其各种共聚物的应用，这些共聚物用于改变其物理和机械性能。在后半部分，详细讨论了用于制造生物材料的各种工艺。最后，介绍了目前在生物医学领域使用的生物材料（支架、药物输送、组织工程、医学植入物、皮肤、化妆品、医学手术和人体植入物），并分别介绍了它们在生物材料领域的优势。
