Department of Radiology, Seoul National University Hospital, Seoul, Korea.
Department of Radiology, Seoul National University College of Medicine, Seoul, Korea.
Korean J Radiol. 2023 Feb;24(2):86-94. doi: 10.3348/kjr.2022.0600.
To compare Octopus multipurpose (MP) electrodes, which are capable of saline instillation and direct tissue temperature measurement, and conventional electrodes for radiofrequency ablation (RFA) in porcine livers .
Sixteen pigs were used in this study. In the first experiment, RFA was performed in the liver for 6 minutes using Octopus MP electrodes (n = 15 ablation zones) and conventional electrodes (n = 12 ablation zones) to investigate the effect of saline instillation. The ablation energy, electrical impedance, and ablation volume of the two electrodes were compared. In the second experiment, RFA was performed near the gallbladder (GB) and colon using Octopus MP electrodes (n = 12 ablation zones for each) with direct tissue temperature monitoring and conventional electrodes (n = 11 ablation zones for each). RFA was discontinued when the temperature increased to > 60\xe2\x84\x83 in the Octopus MP electrode group, whereas RFA was performed for a total of 6 minutes in the conventional electrode group. Thermal injury was assessed and compared between the two groups by pathological examination.
In the first experiment, the ablation volume and total energy delivered in the Octopus MP electrode group were significantly larger than those in the conventional electrode group (15.7 ± 4.26 cm vs. 12.5 ± 2.14 cm, = 0.027; 5.48 ± 0.49 Kcal vs. 5.04 ± 0.49 Kcal, = 0.029). In the second experiment, thermal injury to the GB and colon was less frequently noted in the Octopus MP electrode group than that in the conventional electrode group (16.7% [2/12] vs. 90.9% [10/11] for GB and 8.3% [1/12] vs. 90.9% [10/11] for colon, < 0.001 for all). The total energy delivered around the GB (2.65 ± 1.07 Kcal vs. 5.04 ± 0.66 Kcal) and colon (2.58 ± 0.57 Kcal vs. 5.17 ± 0.90 Kcal) were significantly lower in the Octopus MP electrode group than that in the conventional electrode group ( < 0.001 for all).
RFA using the Octopus MP electrodes induced a larger ablation volume and resulted in less thermal injury to the adjacent organs compared with conventional electrodes.
比较章鱼多功能（MP）电极，其能够盐水灌注和直接组织温度测量，并在猪肝脏的射频消融（RFA）常规电极。
本研究使用了 16 头猪。在第一个实验中，使用 Octopus MP 电极（n = 15 消融区）和常规电极（n = 12 消融区）在肝脏中进行 6 分钟的 RFA，以研究盐水灌注的效果。比较了两种电极的消融能量、电阻和消融体积。在第二个实验中，使用 Octopus MP 电极（n = 12 个消融区）直接组织温度监测和常规电极（n = 11 个消融区）在胆囊（GB）和结肠附近进行 RFA。当 Octopus MP 电极组的温度升高到> 60℃时，停止 RFA，而常规电极组总共进行 6 分钟的 RFA。通过病理检查比较两组之间的热损伤。
在第一个实验中，Octopus MP 电极组的消融体积和总能量明显大于常规电极组（15.7 ± 4.26 cm 比 12.5 ± 2.14 cm， = 0.027；5.48 ± 0.49 Kcal 比 5.04 ± 0.49 Kcal， = 0.029）。在第二个实验中，Octopus MP 电极组对 GB 和结肠的热损伤较常规电极组少（GB 为 16.7%[2/12]，常规电极组为 90.9%[10/11]；结肠为 8.3%[1/12]，常规电极组为 90.9%[10/11]，所有 < 0.001）。GB 周围的总能量（2.65 ± 1.07 Kcal 比 5.04 ± 0.66 Kcal）和结肠（2.58 ± 0.57 Kcal 比 5.17 ± 0.90 Kcal）的传递量Octopus MP 电极组明显低于常规电极组（所有 < 0.001）。
与常规电极相比，使用 Octopus MP 电极进行 RFA 可产生更大的消融体积，并减少对邻近器官的热损伤。
