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花色苷:肥胖症和 2 型糖尿病的潜在治疗方法。

Anthocyanins: Potential Therapeutic Approaches towards Obesity and Diabetes Mellitus Type 2.

机构信息

Centro de Investigación en Ciencias de la Salud (CICSA), Facultad de Ciencias de la Salud, Universidad Anáhuac México, Huixquilucan 52786, Mexico.

Instituto para la Investigación en Obesidad, Instituto Tecnológico y de Estudios Superiores de Monterrey, Campus Guadalajara, Guadalajara 64849, Mexico.

出版信息

Molecules. 2023 Jan 27;28(3):1237. doi: 10.3390/molecules28031237.

Abstract

Overweight and obesity are present in about three-quarters of the adult population in Mexico. The inflammatory mechanisms subjacent to visceral white adipose tissue are accountable for the initiation and development of cardiometabolic alterations, including type 2 diabetes. Lifestyle changes are pillars within its therapeutics and, thus, current dietary modifications should include not only hypocaloric prescriptions with balanced macronutrient intake, preferably by increasing the amount of whole grains, fruits, vegetables, nuts and legumes, but in concomitance, bioactive substances, such as anthocyanins, have been correlated with lower incidence of this disease.

摘要

超重和肥胖在墨西哥约有四分之三的成年人口中存在。内脏白色脂肪组织中潜在的炎症机制是引发和发展心血管代谢异常的原因,包括 2 型糖尿病。生活方式的改变是其治疗的基础,因此,目前的饮食调整不仅应包括低热量的处方和平衡的宏量营养素摄入,最好是通过增加全谷物、水果、蔬菜、坚果和豆类的摄入量,而且还应同时摄入生物活性物质,如花青素,与这种疾病的较低发病率相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1bc/9919338/d3e3c87440bf/molecules-28-01237-g001.jpg

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