利用一种生长抑制性单克隆抗体对引起山羊传染性胸膜肺炎的F38支原体进行鉴别
Differentiation of F38 mycoplasmas causing contagious caprine pleuropneumonia with a growth-inhibiting monoclonal antibody.
作者信息
Rurangirwa F R, McGuire T C, Musoke A J, Kibor A
机构信息
Department of Veterinary Microbiology and Pathology, Washington State University, Pullman 99164.
出版信息
Infect Immun. 1987 Dec;55(12):3219-20. doi: 10.1128/iai.55.12.3219-3220.1987.
Abstract
Monoclonal antibody WM-25 inhibited the in vitro growth of 13 F38 isolates from goats with contagious caprine pleuropneumonia but not 7 heterologous mycoplasma isolates representing four different species. In contrast to results with polyclonal antisera, growth inhibition by monoclonal antibody WM-25 was specific for F38 mycoplasma isolates and constituted a reliable means of distinguishing F38 from other mycoplasmas.
摘要
单克隆抗体WM - 25抑制了13株来自患传染性山羊胸膜肺炎山羊的F38分离株的体外生长，但对代表4个不同物种的7株异源支原体分离株没有抑制作用。与多克隆抗血清的结果相反，单克隆抗体WM - 25的生长抑制作用对F38支原体分离株具有特异性，是区分F38与其他支原体的可靠方法。
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