Khayat Maan T, Alharbi Majed, Ghazawi Kholoud F, Mohamed Gamal A, Ibrahim Sabrin R M
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Clinical Pharmacy Department, College of Pharmacy, Umm Al-Qura University, Makkah 24382, Saudi Arabia.
Plants (Basel). 2023 Feb 16;12(4):902. doi: 10.3390/plants12040902.
is the third largest genus of the Apiaceae family, its species are utilized as a remedy for diverse ailments all over the world. K. M. Shen (Chou-AWei, Chinese ) is mainly found in Xin-jiang Uygur Autonomous Region, China. Traditionally, it is utilized for treating various illnesses such as digestive disorders, rheumatoid arthritis, wound infection, baldness, bronchitis, ovarian cysts, intestinal worms, diarrhea, malaria, abdominal mass, cold, measles, and bronchitis. It can produce different classes of metabolites such as sesquiterpene coumarins, steroidal esters, lignans, phenylpropanoids, sesquiterpenes, monoterpenes, coumarins, organic acid glycosides, and sulfur-containing compounds with prominent bioactivities. The objective of this work is to point out the reported data on including traditional uses, phytoconstituents, biosynthesis, and bioactivities. In the current work, 194 metabolites were reported from in the period from 1987 to the end of 2022. Nevertheless, future work should be directed to conduct , mechanistic, and clinical assessments of this plant`s metabolites to confirm its safe usage.
是伞形科的第三大属,其物种在世界各地被用作治疗多种疾病的药物。K. M. Shen(周阿伟,中文)主要分布在中国新疆维吾尔自治区。传统上,它被用于治疗各种疾病,如消化系统疾病、类风湿性关节炎、伤口感染、脱发、支气管炎、卵巢囊肿、肠道寄生虫、腹泻、疟疾、腹部肿块、感冒、麻疹和支气管炎。它能产生不同种类的代谢产物,如倍半萜香豆素、甾体酯、木脂素、苯丙素类、倍半萜、单萜、香豆素、有机酸糖苷和具有显著生物活性的含硫化合物。这项工作的目的是指出关于其传统用途、植物成分、生物合成和生物活性等方面的报道数据。在当前工作中,1987年至2叭2年底期间从该属植物中报道了194种代谢产物。然而,未来的工作应致力于对该植物代谢产物进行药效学、作用机制和临床评估,以确认其安全使用性。