Choi Youngjin, Lee Hongchul
School of Industrial Management Engineering, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul 02841, Republic of Korea.
Biomed Signal Process Control. 2023 Jul;84:104695. doi: 10.1016/j.bspc.2023.104695. Epub 2023 Mar 2.
Lung diseases lead to complications from obstructive diseases, and the COVID-19 pandemic has increased lung disease-related deaths. Medical practitioners use stethoscopes to diagnose lung disease. However, an artificial intelligence model capable of objective judgment is required since the experience and diagnosis of respiratory sounds differ. Therefore, in this study, we propose a lung disease classification model that uses an attention module and deep learning. Respiratory sounds were extracted using log-Mel spectrogram MFCC. Normal and five types of adventitious sounds were effectively classified by improving VGGish and adding a light attention connected module to which the efficient channel attention module (ECA-Net) was applied. The performance of the model was evaluated for accuracy, precision, sensitivity, specificity, f1-score, and balanced accuracy, which were 92.56%, 92.81%, 92.22%, 98.50%, 92.29%, and 95.4%, respectively. We confirmed high performance according to the attention effect. The classification causes of lung diseases were analyzed using gradient-weighted class activation mapping (Grad-CAM), and the performances of their models were compared using open lung sounds measured using a Littmann 3200 stethoscope. The experts' opinions were also included. Our results will contribute to the early diagnosis and interpretation of diseases in patients with lung disease by utilizing algorithms in smart medical stethoscopes.
肺部疾病会引发阻塞性疾病并发症,而新冠疫情增加了与肺部疾病相关的死亡人数。医生使用听诊器来诊断肺部疾病。然而,由于呼吸音的经验和诊断存在差异,因此需要一个能够进行客观判断的人工智能模型。因此,在本研究中,我们提出了一种使用注意力模块和深度学习的肺部疾病分类模型。使用对数梅尔频谱图MFCC提取呼吸音。通过改进VGGish并添加应用了高效通道注意力模块(ECA-Net)的轻量级注意力连接模块,有效地对正常呼吸音和五种类型的附加音进行了分类。对该模型的性能进行了评估,其准确率、精确率、灵敏度、特异性、F1分数和平衡准确率分别为92.56%、92.81%、92.22%、98.50%、92.29%和95.4%。我们根据注意力效应证实了该模型具有高性能。使用梯度加权类激活映射(Grad-CAM)分析了肺部疾病的分类原因,并使用Littmann 3200听诊器测量的开放肺音比较了模型的性能。研究还纳入了专家意见。我们的研究结果将通过在智能医用听诊器中利用算法,为肺部疾病患者的疾病早期诊断和解读做出贡献。