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基于磁共振成像的脑肿瘤图像分割的改进迁移学习方法

Magnetic Resonance Imaging Image-Based Segmentation of Brain Tumor Using the Modified Transfer Learning Method.

作者信息

Singh Sandeep, Singh Benoy Kumar, Kumar Anuj

机构信息

Department of Physics, GLA University, Mathura, Uttar Pradesh, India.

Department of Radiation Oncology, Lady Hardinge Medical College and Associated Hospitals, New Delhi, India.

出版信息

J Med Phys. 2022 Oct-Dec;47(4):315-321. doi: 10.4103/jmp.jmp_52_22. Epub 2023 Jan 10.

Abstract

PURPOSE

The goal of this study was to improve overall brain tumor segmentation (BraTS) accuracy. In this study, a form of convolutional neural network called three-dimensional (3D) U-Net was utilized to segment various tumor regions on brain 3D magnetic resonance imaging images using a transfer learning technique.

MATERIALS AND METHODS

The dataset used for this study was obtained from the multimodal BraTS challenge. The total number of studies was 2240, obtained from BraTS 2018, BraTS 2019, BraTS 2020, and BraTS 2021 challenges, and each study had five series: T1, contrast-enhanced-T1, Flair, T2, and segmented mask file (seg), all in Neuroimaging Informatics Technology Initiative (NIFTI) format. The proposed method employs a 3D U-Net that was trained separately on each of the four datasets by transferring weights across them.

RESULTS

The overall training accuracy, validation accuracy, mean dice coefficient, and mean intersection over union achieved were 99.35%, 98.93%, 0.9875%, and 0.8738%, respectively.

CONCLUSION

The proposed method for tumor segmentation outperforms the existing method.

摘要

目的

本研究的目标是提高整体脑肿瘤分割(BraTS)的准确性。在本研究中,一种名为三维(3D)U-Net的卷积神经网络形式被用于利用迁移学习技术在脑三维磁共振成像图像上分割各种肿瘤区域。

材料与方法

本研究使用的数据集来自多模态BraTS挑战赛。研究总数为2240个,取自BraTS 2018、BraTS 2019、BraTS 2020和BraTS 2021挑战赛,每个研究有五个序列:T1、增强T1、Flair、T2和分割掩码文件(seg),均为神经影像信息学技术倡议(NIFTI)格式。所提出的方法采用了一个3D U-Net,通过在四个数据集中转移权重分别对每个数据集进行训练。

结果

实现的总体训练准确率、验证准确率、平均骰子系数和平均交并比分别为99.35%、98.93%、0.9875%和0.8738%。

结论

所提出的肿瘤分割方法优于现有方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e3b/9997534/072cd67b3e5d/JMP-47-315-g001.jpg

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