Mainland Hospital Yaba Lagos Nigeria.
Nigeria Centre for Disease Control. Nigeria Field Epidemiology and Laboratory Training Program Abuja Nigeria.
Afr Health Sci. 2022 Sep;22(3):486-494. doi: 10.4314/ahs.v22i3.52.
Lagos State has the highest burden of COVID-19 in Nigeria. We assessed associated factors with death from COVID-19 among hospitalized patients in Lagos, Nigeria.
A retrospective cross-sectional study was conducted using de-identified records of laboratory-confirmed COVID-19 patients admitted into 15 isolation centers in Lagos State between February 27, 2020, and September 30, 2020.
A total of 2,858 COVID -19 patients were included in this study. The mean age of the patients was 41.9±15.5 years. A higher proportion of patients were males (65.8%), asymptomatic (55.5%), had no comorbid condition (72.2%) and had the mild disease (73.8%). The case fatality rate was 6.5%. The odds of death from COVID-19 infection increased by 4% with every increase in age (AOR 1.04, 95%CI 1.03-1.05, p<0.001). The chance of dying was 50% fold more among males (AOR 1.5, 95%CI 1.0 - 2.2, p = 0.042), 60% fold more among patients with comorbidity (AOR 1.6, 95%CI 1.3 - 2.4, p = 0.037) and 9 fold more among patients with severe COVID-19 infection (AOR 9.6, 95% CI 4.9 - 19.1, p <0.001).
The odds of dying was higher among males, the elderly, patients with comorbidity and severe COVID-19.
拉各斯州是尼日利亚 COVID-19 负担最重的州。我们评估了与尼日利亚拉各斯州住院患者 COVID-19 死亡相关的因素。
这是一项回顾性的横断面研究，使用了 2020 年 2 月 27 日至 2020 年 9 月 30 日期间在拉各斯州 15 个隔离中心住院的实验室确诊 COVID-19 患者的匿名记录。
本研究共纳入 2858 例 COVID-19 患者。患者的平均年龄为 41.9±15.5 岁。较高比例的患者为男性（65.8%）、无症状（55.5%）、无合并症（72.2%）和轻度疾病（73.8%）。COVID-19 的病死率为 6.5%。年龄每增加 1 岁，COVID-19 感染死亡的几率增加 4%（OR 1.04，95%CI 1.03-1.05，p<0.001）。男性死亡的几率是女性的 1.5 倍（OR 1.5，95%CI 1.0-2.2，p = 0.042），有合并症的患者死亡的几率是无合并症的 1.6 倍（OR 1.6，95%CI 1.3-2.4，p = 0.037），重症 COVID-19 感染患者死亡的几率是轻症患者的 9 倍（OR 9.6，95%CI 4.9-19.1，p <0.001）。
男性、老年人、有合并症和重症 COVID-19 患者死亡的几率更高。
