Akram Noor, Saeed Farhan, Afzaal Muhammad, Shah Yasir Abbas, Qamar Aiza, Faisal Zargham, Ghani Samia, Ateeq Huda, Akhtar Muhammad Nadeem, Tufail Tabassum, Hussain Muzzamal, Asghar Aasma, Rasheed Ammara, Jbawi Entessar Al
Department of Food and Nutrition Government College University Faisalabad Pakistan.
Department of Food Science Government College University Faisalabad Pakistan.
Food Sci Nutr. 2023 Jan 11;11(3):1166-1177. doi: 10.1002/fsn3.3162. eCollection 2023 Mar.
The Coronavirus disease 2019 (COVID-19) has spread across the globe and is causing widespread disaster. The impact of gut microbiota on lung disease has been widely documented. Diet, environment, and genetics all play a role in shaping the gut microbiota, which can influence the immune system. Improving the gut microbiota profile through customized diet, nutrition, and supplementation has been shown to boost immunity, which could be one of the preventative methods for reducing the impact of various diseases. Poor nutritional status is frequently linked to inflammation and oxidative stress, both of which can affect the immune system. This review emphasizes the necessity of maintaining an adequate level of important nutrients to effectively minimize inflammation and oxidative stress, moreover to strengthen the immune system during the COVID-19 severity. Furthermore, the purpose of this review is to present information and viewpoints on the use of probiotics, prebiotics, and synbiotics as adjuvants for microbiota modification and its effects on COVID-19 prevention and treatment.
2019年冠状病毒病（COVID-19）已在全球蔓延并造成广泛灾难。肠道微生物群对肺部疾病的影响已有广泛记载。饮食、环境和基因在塑造肠道微生物群方面均发挥作用，而肠道微生物群会影响免疫系统。通过定制饮食、营养补充来改善肠道微生物群特征已被证明可增强免疫力，这可能是减轻各种疾病影响的预防方法之一。营养状况不佳常与炎症和氧化应激相关，二者均可影响免疫系统。本综述强调，在COVID-19疫情严峻时期，维持重要营养素的充足水平对于有效减轻炎症和氧化应激、进而增强免疫系统的必要性。此外，本综述旨在介绍有关使用益生菌、益生元及合生元作为调节微生物群佐剂及其对COVID-19预防和治疗效果的信息和观点。
