Department of Dermatology, Venereology and Allergology, Wrocław Medical University, 50-368 Wrocław, Poland.
Cells. 2023 Mar 21;12(6):951. doi: 10.3390/cells12060951.
Androgenetic alopecia is a condition that results in hair loss in both men and women. This can have a significant impact on a person's psychological well-being, which can lead to a decreased quality of life. We conducted a systematic review to evaluate the efficacy of using stem cells in androgenic alopecia. The search was conducted in MEDLINE via PubMed, Web of Science, and Scopus databases. The review was performed on data pertaining to the efficacy of using different types of stem cells in androgenic alopecia: quantitative results of stem cell usage were compared to the control treatment or, different types of treatment for female and male androgenetic alopecia. Of the outcomes, the density of hair was analyzed. Fourteen articles were selected for this review. During and after treatment with stem cells, no major side effects were reported by patients with alopecia. The use of stem cells in androgenic alopecia seems to be a promising alternative to the standard treatment or it could play the role of complementary therapy to improve the effect of primary treatment. However, these results should be interpreted with caution until they can be reproduced in larger and more representative samples.
男性型脱发是一种导致男性和女性脱发的病症。这会对一个人的心理健康产生重大影响，导致生活质量下降。我们进行了一项系统评价，以评估使用干细胞治疗雄激素性脱发的疗效。检索了 MEDLINE 通过 PubMed、Web of Science 和 Scopus 数据库。这项综述是关于使用不同类型的干细胞治疗雄激素性脱发的疗效的数据：将干细胞使用的定量结果与对照治疗或女性和男性雄激素性脱发的不同类型治疗进行比较。在分析的结果中，对头发密度进行了分析。本综述共纳入了 14 篇文章。在接受干细胞治疗期间和之后，脱发患者没有报告出现重大副作用。在雄激素性脱发中使用干细胞似乎是标准治疗的一种有前途的替代方法，或者它可以作为补充治疗来提高主要治疗的效果。然而，在更大、更具代表性的样本中重现这些结果之前，这些结果应谨慎解释。
