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通过深度学习增强微波成像进行热疗监测:数值评估

Hyperthermia Treatment Monitoring via Deep Learning Enhanced Microwave Imaging: A Numerical Assessment.

作者信息

Yago Ruiz Álvaro, Cavagnaro Marta, Crocco Lorenzo

机构信息

CNR-IREA National Research Council of Italy, Institute for Electromagnetic Sensing of the Environment, 80124 Naples, Italy.

Department of Information Engineering, Electronics, and Telecommunications, University of Rome "La Sapienza", 00184 Rome, Italy.

出版信息

Cancers (Basel). 2023 Mar 11;15(6):1717. doi: 10.3390/cancers15061717.

DOI:10.3390/cancers15061717
PMID:36980603
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10046415/
Abstract

The paper deals with the problem of monitoring temperature during hyperthermia treatments in the whole domain of interest. In particular, a physics-assisted deep learning computational framework is proposed to provide an objective assessment of the temperature in the target tissue to be treated and in the healthy one to be preserved, based on the measurements performed by a microwave imaging device. The proposed concept is assessed in-silico for the case of neck tumors achieving an accuracy above 90%. The paper results show the potential of the proposed approach and support further studies aimed at its experimental validation.

摘要

本文探讨了在整个感兴趣区域内进行热疗治疗时的温度监测问题。具体而言,提出了一种物理辅助的深度学习计算框架,以基于微波成像设备所进行的测量,对待治疗的目标组织和要保留的健康组织中的温度提供客观评估。针对颈部肿瘤的情况,在计算机模拟中对所提出的概念进行了评估,其准确率达到了90%以上。论文结果显示了所提方法的潜力,并支持旨在对其进行实验验证的进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f5a/10046415/f3df3875463a/cancers-15-01717-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f5a/10046415/e57daafec967/cancers-15-01717-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f5a/10046415/006e75d4a23d/cancers-15-01717-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f5a/10046415/53b07926f333/cancers-15-01717-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f5a/10046415/0a465278349e/cancers-15-01717-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f5a/10046415/29d5a3e0fa13/cancers-15-01717-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f5a/10046415/681b38ae6944/cancers-15-01717-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f5a/10046415/f3df3875463a/cancers-15-01717-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f5a/10046415/e57daafec967/cancers-15-01717-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f5a/10046415/006e75d4a23d/cancers-15-01717-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f5a/10046415/53b07926f333/cancers-15-01717-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f5a/10046415/0a465278349e/cancers-15-01717-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f5a/10046415/29d5a3e0fa13/cancers-15-01717-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f5a/10046415/681b38ae6944/cancers-15-01717-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f5a/10046415/f3df3875463a/cancers-15-01717-g007.jpg

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本文引用的文献

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A review of some techniques for inclusion of domain-knowledge into deep neural networks.综述:将领域知识纳入深度神经网络的一些技术。
Sci Rep. 2022 Jan 20;12(1):1040. doi: 10.1038/s41598-021-04590-0.
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A Novel Approach on Microwave Hyperthermia.一种微波热疗的新方法。
Diagnostics (Basel). 2021 Mar 10;11(3):493. doi: 10.3390/diagnostics11030493.
3
Differences in the dielectric properties of various benign and malignant thyroid nodules.各种良性和恶性甲状腺结节的介电特性差异。
Med Phys. 2021 Feb;48(2):760-769. doi: 10.1002/mp.14562. Epub 2020 Dec 16.
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Heating technology for malignant tumors: a review.加热技术治疗恶性肿瘤:综述。
Int J Hyperthermia. 2020;37(1):711-741. doi: 10.1080/02656736.2020.1779357.
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Ultra-Wideband Temperature Dependent Dielectric Spectroscopy of Porcine Tissue and Blood in the Microwave Frequency Range.猪组织和血液在微波频段的超宽带温度相关介电谱。
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