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单侧埋藏性视盘小疣引发年轻患者的视网膜中央静脉阻塞——发现一种被忽视的病症。

Unilateral buried optic nerve head drusen triggering central retinal vein occlusion in young - Discovering an eclipsed entity.

作者信息

Vallinayagam Muthu Krishnan, Koushik S, Vaithianathan Amirtha, Sainath Dipika

机构信息

Department of Ophthalmology, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth, Puducherry, India.

出版信息

Oman J Ophthalmol. 2022 Dec 12;16(1):113-116. doi: 10.4103/ojo.ojo_85_21. eCollection 2023 Jan-Apr.

DOI:10.4103/ojo.ojo_85_21
PMID:37007233
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10062086/
Abstract

Optic nerve head (ONH) drusen are acellular calcified concretions. Buried drusen manifests as pseudopapilledema. The compressive effects of ONH drusen can rarely precipitate central retinal vein occlusion (CRVO). The superimposition of pseudopapilledema on disc edema in CRVO poses a diagnostic dilemma. A 40-year-old female without systemic comorbidities presented with resolving CRVO. An exhaustive systemic workup revealed no abnormalities. Ultrasonography demonstrated buried ONH drusen. This unusual etiology must be considered in a young patient in the absence of systemic risk factors, persistence of "nasally conspicuous" disc elevation, and presence of peripapillary hemorrhages. Ultrasonography must be incorporated in the diagnostic armamentarium in a young patient with CRVO.

摘要

视神经乳头(ONH)玻璃疣是无细胞的钙化凝结物。埋藏性玻璃疣表现为假性视乳头水肿。ONH玻璃疣的压迫作用很少会引发视网膜中央静脉阻塞(CRVO)。CRVO中假性视乳头水肿与视盘水肿的叠加造成了诊断困境。一名无全身性合并症的40岁女性出现CRVO缓解情况。全面的全身检查未发现异常。超声检查显示有埋藏性ONH玻璃疣。在没有全身性危险因素、“鼻侧明显”视盘隆起持续存在以及视乳头周围出血的年轻患者中,必须考虑这种不寻常的病因。对于患有CRVO的年轻患者,超声检查必须纳入诊断手段中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34d6/10062086/22d09b40034c/OJO-16-113-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34d6/10062086/eb37f0ae9ea4/OJO-16-113-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34d6/10062086/fca3bf9136bc/OJO-16-113-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34d6/10062086/c82efeb5e00e/OJO-16-113-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34d6/10062086/22d09b40034c/OJO-16-113-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34d6/10062086/eb37f0ae9ea4/OJO-16-113-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34d6/10062086/fca3bf9136bc/OJO-16-113-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34d6/10062086/c82efeb5e00e/OJO-16-113-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34d6/10062086/22d09b40034c/OJO-16-113-g004.jpg

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本文引用的文献

1
Acute Unilateral Anterior Ischemic Optic Neuropathy Secondary to Optic Nerve Head Drusen: Report of a Rare Coexistence.视神经乳头 drusen 继发急性单侧前部缺血性视神经病变:罕见并存情况报告
Neuroophthalmology. 2018 Sep 19;43(5):330-333. doi: 10.1080/01658107.2018.1520900. eCollection 2019 Nov.
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Optic disc drusen precipitating central retinal vein occlusion in young.视盘玻璃膜疣在年轻人中引发视网膜中央静脉阻塞。
BMJ Case Rep. 2019 Jul 8;12(7):e230677. doi: 10.1136/bcr-2019-230677.
3
Optic Nerve Head Drusen: An Update.视神经乳头 drusen:最新进展。 (注:这里“drusen”一般译为“玻璃膜疣”,但直接保留原文未翻译,因为不太明确其在特定语境下是否有特殊含义或需要特别处理。)
Neuroophthalmology. 2018 Apr 25;42(6):367-384. doi: 10.1080/01658107.2018.1444060. eCollection 2018 Dec.
4
Bilateral disc drusen in a diabetic patient simulating diabetic papillopathy as a cause of disc edema.一名糖尿病患者双侧视盘玻璃膜疣,酷似糖尿病性视乳头病变,为视盘水肿的病因。
Indian J Ophthalmol. 2017 Oct;65(10):1051-1053. doi: 10.4103/ijo.IJO_355_17.
5
A Rare Cause of Unilateral Central Retinal Vein Occlusion in a Young Patient: Type III Mixed Cryoglobulinemia.一名年轻患者单侧视网膜中央静脉阻塞的罕见病因:III型混合性冷球蛋白血症
Case Rep Ophthalmol Med. 2016;2016:1949362. doi: 10.1155/2016/1949362. Epub 2016 Jun 23.
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Case report of optic disc drusen with simultaneous peripapillary subretinal hemorrhage and central retinal vein occlusion.视盘玻璃疣合并视乳头周围视网膜下出血及视网膜中央静脉阻塞的病例报告
Case Rep Ophthalmol Med. 2014;2014:156178. doi: 10.1155/2014/156178. Epub 2014 Dec 2.
7
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