Łabuz Grzegorz, Yan Weijia, Baur Isabella D, Khoramnia Ramin, Auffarth Gerd U
Department of Ophthalmology, David J. Apple International Laboratory for Ocular Pathology, Heidelberg University, 69120 Heidelberg, Germany.
J Clin Med. 2023 Mar 27;12(7):2523. doi: 10.3390/jcm12072523.
Presbyopia correction through implantation of a trifocal intraocular lens (IOL) is a modality offered to both cataract and refractive-lens exchange patients. To maximize postoperative satisfaction, IOL selection needs to be made based on patients' requirements aligned with the available technology. Five Trifocal IOLs were assessed in this study, and their differentiating features were identified: Triumf POD L GF, AT Lisa Tri, Tecnis Synergy, AcrySof IQ PanOptix, and Acriva Trinova Pro C. The optical quality was assessed using the modulation-transfer-function principle. Simulated defocus curves were derived from a non-linear formula. Far-focus simulated visual acuity (simVA) was 0.03 logMAR or better for all the studied IOLs, showing minimal differences. However, each IOL's intermediate focus position differed across a range from 61 cm to 80 cm; and for the near focus, it was 36 cm to 44 cm. Triumf demonstrated improved intermediate point at the expense of the near focus resulting in a lower predicted near VA. PanOptix exhibited the shortest range of vision without a clear distinction between intermediate and near-point. The remaining lenses presented three foci of comparable optical quality and, thus, simVA performance. Each model, however, revealed a different aperture-change response. Trinova function improved at intermediate but was worse at near for larger pupils. The opposite was observed for AT Lisa. Synergy's optical quality change was predominantly associated with lower pupil diameter. In conclusion, the trifocal IOLs can be differentiated according to their secondary-foci position, light-energy distribution, and pupil-size-related behavior. The observed differences may translate directly into a clinical effect showing that the trifocal IOLs vary in their ability to deliver optimal vision at different distances, with some providing improved intermediate while others favor reading distance. The knowledge gained through this objective testing can support IOL selection, postoperative patient counselling and increase the chance of spectacle independence after surgery.
通过植入三焦点人工晶状体(IOL)矫正老花眼是一种为白内障和屈光性晶状体置换患者提供的治疗方式。为了最大限度提高术后满意度,需要根据患者需求并结合现有技术来选择人工晶状体。本研究评估了五种三焦点人工晶状体,并确定了它们的区别特征:Triumf POD L GF、AT Lisa Tri、Tecnis Synergy、AcrySof IQ PanOptix和Acriva Trinova Pro C。使用调制传递函数原理评估光学质量。模拟散焦曲线由非线性公式得出。所有研究的人工晶状体的远焦点模拟视力(simVA)均为0.03 logMAR或更好,差异极小。然而,每种人工晶状体的中间焦点位置在61厘米至80厘米范围内各不相同;近焦点位置则在36厘米至44厘米之间。Triumf以牺牲近焦点为代价改善了中间点,导致预测的近视力较低。PanOptix的视力范围最短,中间点和近点之间没有明显区别。其余晶状体呈现出三个光学质量相当的焦点,因此simVA表现相似。然而,每个型号都显示出不同的孔径变化响应。Trinova在中间视力时功能改善,但对于较大瞳孔在近视力时较差。AT Lisa则相反。Synergy的光学质量变化主要与较小瞳孔直径有关。总之,三焦点人工晶状体可以根据其第二焦点位置、光能分布和瞳孔大小相关行为进行区分。观察到的差异可能直接转化为临床效果,表明三焦点人工晶状体在不同距离提供最佳视力的能力各不相同,有些在中间视力方面有所改善,而另一些则更有利于阅读距离。通过这种客观测试获得的知识可以支持人工晶状体的选择、术后患者咨询,并增加术后摆脱眼镜的机会。