流感疫苗对老年人华法林抗凝作用缺乏影响。
Lack of effect of influenza vaccine on warfarin anticoagulation in the elderly.
作者信息
Gomolin I H
出版信息
CMAJ. 1986 Jul 1;135(1):39-41.
Abstract
Influenza vaccine may inhibit hepatic metabolism of drugs and has been reported to prolong the prothrombin time in patients receiving warfarin by affecting the coagulation pathway. In a group of seven elderly residents of a long-term care facility who were receiving warfarin, prolongation of the prothrombin and partial thromboplastin times could not be shown up to 5 weeks after vaccination against influenza. The results were similar in nine elderly subjects who were not receiving warfarin.
摘要
流感疫苗可能会抑制药物的肝脏代谢，并且有报道称，它会通过影响凝血途径延长接受华法林治疗患者的凝血酶原时间。在一组接受华法林治疗的长期护理机构的七名老年居民中，接种流感疫苗后长达5周都未发现凝血酶原时间和部分凝血活酶时间延长。在九名未接受华法林治疗的老年受试者中，结果类似。
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本文引用的文献
1
Depression of aminopyrine metabolism by influenza vaccination.
N Engl J Med. 1981 Nov 19;305(21):1262-4. doi: 10.1056/NEJM198111193052106.
2
Serum theophylline levels after influenza vaccination.流感疫苗接种后的血清茶碱水平。
Can Med Assoc J. 1981 Aug 1;125(3):243-4.
3
Decreased elimination of theophylline after influenza vaccination.流感疫苗接种后茶碱清除率降低。
Can Med Assoc J. 1980 Aug 23;123(4):288-90.
4
Decreased elimination of theophylline after influenza vaccination.流感疫苗接种后茶碱清除率降低。
Can Med Assoc J. 1982 Mar 1;126(5):470.
5
Influenza vaccination and warfarin or theophylline toxicity in nursing-home residents.
N Engl J Med. 1983 Jun 30;308(26):1601-2. doi: 10.1056/NEJM198306303082615.
6
Influenza vaccination and warfarin anticoagulation.流感疫苗接种与华法林抗凝治疗。
Ann Intern Med. 1984 Jun;100(6):835-7. doi: 10.7326/0003-4819-100-6-835.
7
Theophylline clearance. Lack of effect of influenza vaccination and ascorbic acid.茶碱清除率。流感疫苗接种和抗坏血酸的无效作用。
Am Rev Respir Dis. 1984 May;129(5):672-5. doi: 10.1164/arrd.1984.129.5.672.
8
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