Yang Zhihua, Lin Shanshan, Liu Yangxi, Song Zhihui, Ge Zhao, Fan Yujian, Chen Lu, Bi Yingfei, Zhao Zhiqiang, Wang Xianliang, Wang Yi, Mao Jingyuan
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China.
Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Front Pharmacol. 2023 May 31;14:1171119. doi: 10.3389/fphar.2023.1171119. eCollection 2023.
Hypertension has become one of the major public health problems in the world. At present, the pathogenesis of hypertension has still not been completely elucidated. In recent years, an increasing evidence shows that intestinal microecology is closely related to hypertension, which provides a new thinking for the prevention and treatment of hypertension. Traditional Chinese medicine (TCM) has unique advantages in the treatment of hypertension. Taking intestinal microecology as the target, it is possible to interpreting the scientific connotation of TCM prevention and treatment of hypertension by updating the treatment concept of hypertension, so as to improve the therapeutic effect. In our study, the clinical evidence for TCM treatment of hypertension was systematicly summarized. And the relationship among TCM, intestinal microecology and hypertension was analyzed. In addition, the methods by which TCM regulates intestinal microecology to prevent and treat hypertension were presented, to provide new research ideas for prevention and treatment of hypertension.
高血压已成为全球主要的公共卫生问题之一。目前，高血压的发病机制仍未完全阐明。近年来，越来越多的证据表明肠道微生态与高血压密切相关，这为高血压的防治提供了新的思路。中医在高血压治疗方面具有独特优势。以肠道微生态为靶点，通过更新高血压治疗理念，有可能阐释中医防治高血压的科学内涵，从而提高治疗效果。在我们的研究中，系统总结了中医治疗高血压的临床证据。并分析了中医、肠道微生态与高血压之间的关系。此外，还介绍了中医通过调节肠道微生态防治高血压的方法，为高血压的防治提供新的研究思路。
