金黄色葡萄球菌剥脱毒素B基因序列
Sequence of the exfoliative toxin B gene of Staphylococcus aureus.
作者信息
Jackson M P, Iandolo J J
出版信息
J Bacteriol. 1986 Aug;167(2):726-8. doi: 10.1128/jb.167.2.726-728.1986.
Abstract
We sequenced the Staphylococcus aureus exfoliative toxin B gene contained on a 1.7-kilobase HindIII fragment of plasmid pRW001. The gene was located by comparison of the amino acid sequences of open reading frames with the amino-terminal sequence of exfoliative toxin B and the total amino acid composition of the protein (A.D. Johnson, L. Spero, J.S. Cades, and B.T. De Cicco, Infect. Immun. 24:679-684, 1979). The primary translation product consists of 274 amino acids and contains a 31-amino-acid N-terminal peptide presumably necessary for transport.
摘要
我们对质粒pRW001的1.7千碱基HindIII片段上所含的金黄色葡萄球菌剥脱毒素B基因进行了测序。通过将开放阅读框的氨基酸序列与剥脱毒素B的氨基末端序列以及该蛋白质的总氨基酸组成进行比较来定位该基因（A.D. 约翰逊、L. 斯佩罗、J.S. 凯兹和B.T. 德西科，《感染与免疫》24:679 - 684，1979年）。初级翻译产物由274个氨基酸组成，并含有一个31个氨基酸的N末端肽，推测该肽对于转运是必需的。
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