School of Nursing, Wuhan University, Located On No. 115, Donghu Road, , Wuhan, 430071, Hubei Province, China.
Obstetrics and Gynecology Outpatient Clinic, Renmin Hospital of Wuhan University, Located On No.99 Zhang Zhidong Road, Wuchang District, Wuhan, 430060, Hubei, China.
BMC Pregnancy Childbirth. 2023 Jun 22;23(1):466. doi: 10.1186/s12884-023-05785-1.
Reducing preventable adverse maternal and offspring outcomes is a global priority. The causes of adverse maternal and fetal outcomes are complex with multidimensional influencing factors. In addition, the Covid-19 epidemic has had a significant psychological and physical impact on people. China is now stepping into the post-epidemic era. We are curious about the psychological and physical situation of maternity in China at this stage. Therefore, we plan to initiate a prospective longitudinal study to investigate the multidimensional influences and mechanisms that affect maternal and offspring health.
We will recruit eligible pregnant women at Renmin Hospital of Hubei Province, China. The expected sample size is 1490. We will assess socio-demographics, Covid-19 related information, social capital, sleep, mental health and medical records, including clinical examination and biochemical tests. Eligible pregnant women will be enrolled in the study with less than 14 weeks of gestation. Participants will receive a total of nine follow-up visits between mid-pregnancy and one year postpartum. The offspring will be followed up at birth, 6 weeks, 3 months, 6 months and one year. In addition, a qualitative study will be conducted to understand the underlying causes that affect maternal and offspring health outcomes.
This is the first longitudinal study of maternity in Wuhan, Hubei Province which integrates physical, psychological and social capital dimensions. Wuhan is the first city to be affected by Covid-19 in China. As China moves into the post-epidemic era, this study will provide us with a better understanding of the long-term impact of the epidemic on maternal and offspring health outcomes. We will implement a range of rigorous measures to enhance participants' retention rate and ensure the quality of data. The study will provide empirical results for maternal health in the post-epidemic era.
降低可预防的母婴不良结局是全球优先事项。母婴不良结局的原因复杂，存在多维度影响因素。此外，新冠疫情对人们的身心造成了重大影响。中国现已步入后疫情时代，我们对现阶段中国母婴的身心状况感到好奇。因此，我们计划开展一项前瞻性纵向研究，以调查影响母婴健康的多维影响因素和机制。
我们将在湖北省人民医院招募符合条件的孕妇。预计样本量为 1490 名。我们将评估社会人口统计学、新冠相关信息、社会资本、睡眠、心理健康和病历，包括临床检查和生化检查。符合条件的孕妇将在妊娠 14 周之前入组研究。参与者将在妊娠中期至产后一年期间接受总共 9 次随访。在出生、6 周、3 个月、6 个月和 1 岁时将对后代进行随访。此外，还将开展定性研究，以了解影响母婴健康结局的潜在原因。
这是首次在湖北省武汉市开展的包含身体、心理和社会资本维度的母婴纵向研究。武汉是中国受新冠疫情影响的第一座城市。随着中国步入后疫情时代，这项研究将使我们更好地了解疫情对母婴健康结局的长期影响。我们将采取一系列严格措施，提高参与者的保留率并确保数据质量。该研究将为后疫情时代的母婴健康提供实证结果。
