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使用具有多层滤波器的 3 维深度卷积神经网络对肺癌 CT 图像进行分类。

Classification of lung cancer computed tomography images using a 3-dimensional deep convolutional neural network with multi-layer filter.

机构信息

Maulana Azad National Institute of Technology, Bhopal, 462003, India.

出版信息

J Cancer Res Clin Oncol. 2023 Oct;149(13):11279-11294. doi: 10.1007/s00432-023-04992-9. Epub 2023 Jun 27.

Abstract

Lung cancer creates pulmonary nodules in the patient's lung, which may be diagnosed early on using computer-aided diagnostics. A novel automated pulmonary nodule diagnosis technique using three-dimensional deep convolutional neural networks and multi-layered filter has been presented in this paper. For the suggested automated diagnosis of lung nodule, volumetric computed tomographic images are employed. The proposed approach generates three-dimensional feature layers, which retain the temporal links between adjacent slices of computed tomographic images. The use of several activation functions at different levels of the proposed network results in increased feature extraction and efficient classification. The suggested approach divides lung volumetric computed tomography pictures into malignant and benign categories. The suggested technique's performance is evaluated using three commonly used datasets in the domain: LUNA 16, LIDC-IDRI, and TCIA. The proposed method outperforms the state-of-the-art in terms of accuracy, sensitivity, specificity, F-1 score, false-positive rate, false-negative rate, and error rate.

摘要

肺癌在患者肺部产生肺结节,可通过计算机辅助诊断尽早诊断。本文提出了一种使用三维深度卷积神经网络和多层滤波器的新型自动化肺结节诊断技术。为了对肺结节进行自动诊断,使用了容积计算机断层扫描图像。所提出的方法生成三维特征层,保留了计算机断层扫描图像的相邻切片之间的时间链接。在网络的不同级别使用多个激活函数可以提高特征提取和有效分类的能力。所提出的方法将肺容积计算机断层扫描图像分为恶性和良性两类。该方法使用该领域中三个常用的数据集(LUNA 16、LIDC-IDRI 和 TCIA)进行性能评估。在准确性、灵敏度、特异性、F1 分数、假阳性率、假阴性率和错误率方面,所提出的方法优于现有技术。

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