慢性酒精中毒患者的视觉诱发电位
Visual evoked responses in chronic alcoholics.
作者信息
Chan Y W, McLeod J G, Tuck R R, Walsh J C, Feary P A
出版信息
J Neurol Neurosurg Psychiatry. 1986 Aug;49(8):945-50. doi: 10.1136/jnnp.49.8.945.
Abstract
Visual evoked responses (VERs) were recorded on 52 chronic alcoholics patients without Wernicke-Korsakoff syndrome, 22 of whom had cerebellar ataxia, and eight chronic alcoholics with Wernicke-Korsakoff syndrome. Abnormal VERs were found in 23% of patients without and 37% of patients with Wernicke-Korsakoff syndrome. The main VER abnormalities of all the alcoholic groups were prolonged latency and reduced amplitude of the P100 component. Improvement followed a six month period of abstinence. VERs may be useful in the early detection of alcohol induced brain damage, and in following the progress of patients with the condition.
摘要
对52名无韦尼克-科尔萨科夫综合征的慢性酒精中毒患者进行了视觉诱发电位（VERs）记录，其中22人患有小脑共济失调，还有8名患有韦尼克-科尔萨科夫综合征的慢性酒精中毒患者。在无韦尼克-科尔萨科夫综合征的患者中，23%发现VER异常，在患有韦尼克-科尔萨科夫综合征的患者中，这一比例为37%。所有酒精中毒组VER的主要异常表现为P100成分潜伏期延长和波幅降低。戒断六个月后情况有所改善。VERs可能有助于早期发现酒精性脑损伤，并跟踪该病症患者的病情进展。
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