Department of Organic Chemistry, Campus Miguel Delibes, University of Valladolid, 47011 Valladolid, Spain.
Mar Drugs. 2023 Jul 13;21(7):402. doi: 10.3390/md21070402.
In this perspective, we showcase the benefits of continuous flow chemistry and photochemistry and how these valuable tools have contributed to the synthesis of organic scaffolds from the marine environment. These technologies have not only facilitated previously described synthetic pathways, but also opened new opportunities in the preparation of novel organic molecules with remarkable pharmacological properties which can be used in drug discovery programs.
在这个视角中,我们展示了连续流动化学和光化学的好处,以及这些有价值的工具如何促进了来自海洋环境的有机支架的合成。这些技术不仅促进了以前描述的合成途径,而且为制备具有显著药理性质的新型有机分子开辟了新的机会,这些分子可用于药物发现计划。