Sharma Kajal, Sharma Meenakshi
Molecular Genetics of Aging, Dr. B.R. Ambedkar Center for Biomedical Research (ACBR), University of Delhi (DU), India.
Environ Res. 2023 Nov 1;236(Pt 2):116826. doi: 10.1016/j.envres.2023.116826. Epub 2023 Aug 4.
The environmental contamination due to bacterial proliferation vs their identification is the major deciding factor in the spread of diseases leading to pandemics. The advent of drug-resistant pathogenic contaminants in our environment has further added to the load of complications associated with their diagnosis and treatment. Obstructing the spread of such infections, prioritizes the expansion of sensor-based diagnostics, effectuating, a sturdy detection of disease-causing microbes, contaminating our surroundings in shortest possible time, with minimal expenditure. Among many sensors known, optical biosensors promote the recognition of pathogens befouling the environment through a comparatively intuitive, brisk, portable, multitudinous, and thrifty approach. This article reviews the recent progresses in optical biosensor-based systems for effective environmental monitoring. The technical and methodological perspectives of fundamental optical-sensing platforms are reviewed, combined with the pros and cons of every procedure. Eventually, the obstacles lying in the path of development of an effective optical biosensor device for bio-monitoring and its future perspectives are highlighted in the present work.
细菌繁殖导致的环境污染与其识别是导致大流行疾病传播的主要决定因素。环境中耐药性病原污染物的出现进一步增加了与其诊断和治疗相关的并发症负担。阻碍此类感染的传播,优先考虑扩展基于传感器的诊断方法,以便在尽可能短的时间内、以最少的费用,对污染我们周围环境的致病微生物进行可靠检测。在众多已知的传感器中,光学生物传感器通过相对直观、快速、便携、多样且经济的方法促进对污染环境的病原体的识别。本文综述了基于光学生物传感器的系统在有效环境监测方面的最新进展。回顾了基本光学传感平台的技术和方法观点,并结合了每个过程的优缺点。最终,本文强调了开发用于生物监测的有效光学生物传感器设备所面临的障碍及其未来前景。