Povshedna Tetiana, Swann Shayda A, Levy Sofia L A, Campbell Amber R, Choinière Manon, Durand Madeleine, Price Colleen, Gill Prubjot, Murray Melanie C M, Côté Hélène C F
Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Centre for Blood Research, University of British Columbia, Vancouver, British Columbia, Canada.
Open Forum Infect Dis. 2023 Jul 15;10(8):ofad350. doi: 10.1093/ofid/ofad350. eCollection 2023 Aug.
Chronic pain is common among people with human immunodeficiency virus (HIV) and detrimental to quality of life and overall health. It is often underdiagnosed, undertreated, and frankly dismissed in women with HIV, despite growing evidence that it is highly prevalent in this population. Thus, we conducted a systematic review and meta-analysis to estimate the global prevalence of chronic pain in women with HIV. The full protocol can be found on PROSPERO (identifier CRD42022301145). Of the 2984 references identified in our search, 36 were included in the systematic review and 35 in the meta-analysis. The prevalence of chronic pain was 31.2% (95% confidence interval [CI], 24.6%-38.7%; = 98% [95% CI, 97%-99%]; < .0001). In this global assessment, we found a high prevalence of chronic pain among women with HIV, underscoring the importance of understanding the etiology of chronic pain, identifying effective treatments, and conducting regular assessments in clinical practice.
慢性疼痛在感染人类免疫缺陷病毒（HIV）的人群中很常见，会对生活质量和整体健康造成损害。尽管越来越多的证据表明慢性疼痛在感染HIV的女性中非常普遍，但它在这些女性中常常被漏诊、治疗不足，甚至被完全忽视。因此，我们进行了一项系统综述和荟萃分析，以估计感染HIV的女性中慢性疼痛的全球患病率。完整方案可在国际前瞻性系统评价注册库（PROSPERO，标识符CRD42022301145）上找到。在我们检索到的2984篇参考文献中，36篇被纳入系统综述，35篇被纳入荟萃分析。慢性疼痛的患病率为31.2%（95%置信区间[CI]，24.6%-38.7%；I² = 98%[95%CI，97%-99%]；P <.0001）。在这项全球评估中，我们发现感染HIV的女性中慢性疼痛的患病率很高，这凸显了在临床实践中了解慢性疼痛病因、确定有效治疗方法以及进行定期评估的重要性。
