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Addict Health. 2022 Jan;14(1):1-6. doi: 10.22122/ahj.v14i1.292.
3
Cognitive dysfunction in schizophrenia: An expert group paper on the current state of the art.精神分裂症中的认知功能障碍:关于当前技术水平的专家小组论文
Schizophr Res Cogn. 2022 Mar 22;29:100249. doi: 10.1016/j.scog.2022.100249. eCollection 2022 Sep.
4
Brain dysfunction of methamphetamine-associated psychosis in resting state: Approaching schizophrenia and critical role of right superior temporal deficit.静息状态下与冰毒相关的精神病的大脑功能障碍:接近精神分裂症和右侧上颞叶缺陷的关键作用
Addict Biol. 2021 Nov;26(6):e13044. doi: 10.1111/adb.13044. Epub 2021 May 6.
5
Study of Methamphetamine Use in Patients Referred to Emergency Ward of a General Hospital at North of Iran in 2017.2017年伊朗北部一家综合医院急诊科收治患者的甲基苯丙胺使用情况研究。
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7
Cognitive deficit in schizophrenia: an overview.精神分裂症认知缺陷:概述。
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8
Attenuation Effect of Cannabinoid Type 1 Receptor Activation on Methamphetamine-Induced Neurodegeneration and Locomotion Impairments among Male Rats.1型大麻素受体激活对雄性大鼠甲基苯丙胺诱导的神经退行性变和运动障碍的衰减作用
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Methamphetamine dependence with and without psychotic symptoms: A multi-modal brain imaging study.有和无精神病症状的甲基苯丙胺依赖:一项多模态脑影像学研究。
Neuroimage Clin. 2018;20:1157-1162. doi: 10.1016/j.nicl.2018.10.023. Epub 2018 Oct 22.
10
A Comparison of Methamphetamine-Induced Psychosis and Schizophrenia: A Review of Positive, Negative, and Cognitive Symptomatology.甲基苯丙胺所致精神病与精神分裂症的比较:阳性、阴性及认知症状学综述
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比较精神分裂症患者、甲基苯丙胺所致精神病患者与健康对照者的认知功能。

Comparing Cognitive Functions in Patients with Schizophrenia and Methamphetamine-Induced Psychosis with Healthy Controls.

作者信息

Eslami Shahrbabaki Mahin, Barfehie Delaram, Mazhari Shahrzad, Ahmadi Atefeh, Shafiee Shahideh

机构信息

Neuroscience Research Center and Institute of Neuropharmacology, Psychiatry Department, Afzalipour School of Medicine, Kerman University of Medical Sciences, Kerman, Iran.

Neurology Research Center, Afzalipour School of Medicine, Kerman University of Medical Sciences, Kerman, Iran.

出版信息

Addict Health. 2022 Oct;14(4):239-243. doi: 10.34172/ahj.2022.1143. Epub 2022 Oct 29.

DOI:10.34172/ahj.2022.1143
PMID:37559792
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10408749/
Abstract

BACKGROUND

There are similar findings about the similarities and differences of cognitive dysfunctions in patients with schizophrenia and methamphetamine-induced psychosis (MIP). This study aimed to compare cognitive functioning in schizophrenia and MIP patients, using a performance-based cognitive assessment battery and an interview-based assessment of cognition.

METHODS

Three groups participated in this study including, (a) 30 patients with MIP, (b) 30 patients with schizophrenia, and (c) 30 healthy individuals. All participants received the Brief Assessment of Cognition in Schizophrenia (BACS), a standardized performance-based cognitive battery, the Schizophrenia Cognition Rating Scale (SCoRS), and the interview-based assessment of cognition.

FINDINGS

Both groups of patients with schizophrenia and MIP performed poorly on all the BACS cognitive domains compared with the healthy controls. The two patient groups were significantly different on the three BACS subscales including verbal fluency, verbal memory, and speed of information processing. Schizophrenia patients performed worse than the MIP group concerning these three subscales. However, the two patient groups were similar in executive function, working memory, and motor speed. Moreover, the SCoRS-informant, SCoRS-global, and PANSS-negative significantly differed between schizophrenia and MIP patients.

CONCLUSION

Although cognitive dysfunctions are mostly similar in patients with MIP and schizophrenia, there are some differences especially in the functions related to prefrontal and temporal lobes.

摘要

背景

关于精神分裂症患者和甲基苯丙胺所致精神病(MIP)患者认知功能障碍的异同有类似的研究结果。本研究旨在使用基于表现的认知评估量表和基于访谈的认知评估,比较精神分裂症患者和MIP患者的认知功能。

方法

三组参与了本研究,包括:(a)30例MIP患者,(b)30例精神分裂症患者,以及(c)30名健康个体。所有参与者均接受了精神分裂症认知简短评估(BACS),这是一种标准化的基于表现的认知量表、精神分裂症认知评定量表(SCoRS)以及基于访谈的认知评估。

结果

与健康对照组相比,精神分裂症患者组和MIP患者组在所有BACS认知领域的表现均较差。两组患者在BACS的三个分量表上存在显著差异,包括言语流畅性、言语记忆和信息处理速度。在这三个分量表上,精神分裂症患者的表现比MIP组更差。然而,两组患者在执行功能、工作记忆和运动速度方面相似。此外,精神分裂症患者和MIP患者在SCoRS informant、SCoRS global和PANSS阴性方面存在显著差异。

结论

虽然MIP患者和精神分裂症患者的认知功能障碍大多相似,但仍存在一些差异,尤其是在与额叶和颞叶相关的功能方面。