Błażejewski Grzegorz, Witkoś Joanna
Faculty of Medicine and Health Science, Andrzej Frycz Modrzewski Krakow University, G. Herlinga-Grudzińskiego, Street 1, 30-705 Kraków, Poland.
J Clin Med. 2023 Jul 29;12(15):4991. doi: 10.3390/jcm12154991.
The COVID-19 pandemic has become the largest and most diverse to threaten the health of humanity since the 1918 influenza pandemic.
This study involved 113 women who had suffered from COVID-19. The study was conducted as interviews with each woman during visits to a clinic prior to the start of their post-COVID-19 physiotherapy treatment cycle. The aim of this study was to assess the prevalence of changes in the women's monthly cycles related to COVID-19, as well as to analyse correlations between dependent variables relating to changes in the monthly cycle and independent variables relating to other factors, such as age, weight, number and type of vaccinations, and time since illness. Additionally, the study assesses correlations between the monthly cycle and COVID-19 symptoms persisting after the illness (long COVID).
Women who reported more symptoms of COVID-19 were more likely to report changes in their menstrual cycle occurring after the SARS-CoV-2 infection, compared with women whose disease course was mild. Women who declared that COVID-19 affected their monthly cycles most often indicated increases in abdominal, lower abdominal, and joint and muscle pain, as well as in the severity of headaches during monthly bleeding. A small percentage of women indicated that their monthly cycles were longer and their regularity disrupted.
This study shows that the more COVID-19 symptoms a woman had, the more often there were noted changes in monthly cycle. The same relationship was also found for persistent long COVID symptoms. The longer the time lapse since the COVID-19 infection, the less frequently changes in the monthly cycle were recorded.
自1918年流感大流行以来，新冠疫情已成为威胁人类健康的规模最大、种类最多的疫情。
本研究纳入了113名感染过新冠的女性。研究通过在她们开始新冠后物理治疗周期之前到诊所就诊时对每位女性进行访谈来开展。本研究的目的是评估与新冠相关的女性月经周期变化的发生率，以及分析与月经周期变化相关的因变量和与其他因素（如年龄、体重、疫苗接种次数和类型以及患病后的时间）相关的自变量之间的相关性。此外，该研究还评估了月经周期与患病后持续存在的新冠症状（新冠后症状）之间的相关性。
与病情较轻的女性相比，报告更多新冠症状的女性更有可能报告在感染SARS-CoV-2后出现月经周期变化。宣称新冠影响其月经周期的女性最常指出腹部、下腹部、关节和肌肉疼痛增加，以及月经期间头痛严重程度增加。一小部分女性表示她们的月经周期变长且规律性受到破坏。
本研究表明，女性感染新冠的症状越多，月经周期变化就越常出现。对于持续存在的新冠后症状也发现了同样的关系。自新冠感染以来的时间间隔越长，记录到月经周期变化的频率就越低。
