Friedman Diabetes Institute, Lenox Hill Hospital, New York, NY, USA.
Institute of Bioelectronic Medicine, Feinstein Institutes for Medical Research, Manhasset, NY, USA.
Adipocyte. 2023 Dec;12(1):2248673. doi: 10.1080/21623945.2023.2248673.
Technologies are transforming the understanding of adipose tissue as a complex and dynamic tissue that plays a critical role in energy homoeostasis and metabolic health. This mini-review provides a brief overview of the potential impact of novel technologies in biomedical research and aims to identify areas where these technologies can make the most significant contribution to adipose tissue research. It discusses the impact of cutting-edge technologies such as single-cell sequencing, multi-omics analyses, spatial transcriptomics, live imaging, 3D tissue engineering, microbiome analysis, imaging, and artificial intelligence/machine learning. As these technologies continue to evolve, we can expect them to play an increasingly important role in advancing our understanding of adipose tissue and improving the treatment of related diseases.
技术正在改变人们对脂肪组织的理解，脂肪组织是一种复杂而动态的组织，在能量平衡和代谢健康中起着关键作用。这篇迷你综述简要概述了新技术在生物医学研究中的潜在影响，并旨在确定这些技术可以在哪些领域为脂肪组织研究做出最重大的贡献。它讨论了单细胞测序、多组学分析、空间转录组学、实时成像、3D 组织工程、微生物组分析、成像和人工智能/机器学习等前沿技术的影响。随着这些技术的不断发展，我们可以预期它们将在提高我们对脂肪组织的理解和改善相关疾病的治疗方面发挥越来越重要的作用。
