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膳食纤维对代谢健康的重要性。

The Importance of Dietary Fiber for Metabolic Health.

作者信息

Bulsiewicz William J

机构信息

PO Box 1757, Mount Pleasant, SC, USA.

出版信息

Am J Lifestyle Med. 2023 Apr 12;17(5):639-648. doi: 10.1177/15598276231167778. eCollection 2023 Sep-Oct.

Abstract

Dietary fiber are non-digestible carbohydrates that are diverse, have varied functions, and are acquired by consuming plant-based foods. Some forms of fiber are digested by the gut microbiota and produce bioactive metabolites called short chain fatty acids-butyrate, acetate, and propionate. Dietary fiber is able to alter human physiology through multiple mechanisms that can result in health benefits. Unfortunately, nearly 19 out of 20 Americans do not consume the minimum recommended amount of fiber each day. This bears profound relevance to public health because at least six of the ten leading causes of death are potentially preventable or clinically improved through dietary means. Additionally, these same conditions share a common underlying pathophysiology-metabolic dysfunction. This can manifest as abdominal obesity, high blood pressure, insulin resistance, dyslipidemia, or collectively as metabolic syndrome. In this review, we will assess the evidence that consumption of dietary fiber undermines these forms of metabolic dysfunction, examine the mechanism of action for these physiologic effects, and consider the potential for dietary fiber to improve human health on a public health level by simply encouraging our patients to consume more plant-based foods in abundance and diversity.

摘要

膳食纤维是不可消化的碳水化合物,种类多样,功能各异,可通过食用植物性食物获取。某些形式的纤维可被肠道微生物群消化,并产生称为短链脂肪酸(丁酸、乙酸和丙酸)的生物活性代谢产物。膳食纤维能够通过多种机制改变人体生理机能,从而带来健康益处。不幸的是,每20个美国人中就有近19人每天摄入的纤维量未达到建议的最低摄入量。这与公共卫生密切相关,因为十大主要死因中至少有六种可通过饮食方式预防或在临床上得到改善。此外,这些疾病有着共同的潜在病理生理学——代谢功能障碍。这可能表现为腹部肥胖、高血压、胰岛素抵抗、血脂异常,或统称为代谢综合征。在本综述中,我们将评估食用膳食纤维可改善这些代谢功能障碍形式的证据,研究这些生理效应的作用机制,并探讨通过鼓励患者大量且多样化地食用植物性食物,膳食纤维在公共卫生层面改善人类健康的潜力。

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