Fernández-Guarino Montserrat, Hernández-Bule Maria Luisa, Bacci Stefano
Dermatology Service, Hospital Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (Irycis), 28034 Madrid, Spain.
Bioelectromagnetic Lab, Hospital Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (Irycis), 28034 Madrid, Spain.
Biomedicines. 2023 Sep 13;11(9):2526. doi: 10.3390/biomedicines11092526.
This review summarizes the recent knowledge of the cellular and molecular processes that occur during wound healing. However, these biological mechanisms have yet to be defined in detail; this is demonstrated by the fact that alterations of events to pathological states, such as keloids, consisting of the excessive formation of scars, have consequences yet to be defined in detail. Attention is also dedicated to new therapies proposed for these kinds of pathologies. Awareness of these scientific problems is important for experts of various disciplines who are confronted with these kinds of presentations daily.
本综述总结了伤口愈合过程中发生的细胞和分子过程的最新知识。然而,这些生物学机制尚未得到详细定义;瘢痕疙瘩等病理状态下事件的改变就证明了这一点,瘢痕疙瘩由过度形成的瘢痕组成,其后果尚未得到详细定义。同时也关注针对这类病症提出的新疗法。认识到这些科学问题对于每天面对这类病症的各学科专家来说很重要。