Zalila-Kolsi Imen, Ben-Mahmoud Afif, Al-Barazie Ray
Faculty of Medical and Health Sciences, Liwa College, Abu Dhabi P.O. Box 41009, United Arab Emirates.
Neurological Disorders Research Center, Qatar Biomedical Research Institute, Hamad Bin Khalifa University, Doha P.O. Box 34110, Qatar.
Microorganisms. 2023 Aug 31;11(9):2215. doi: 10.3390/microorganisms11092215.
, a Gram-positive bacterium, has emerged as a versatile microorganism with significant applications in various fields, including industry, medicine, and agriculture. This comprehensive review aims to provide an in-depth understanding of the characteristics, genetic tools, and metabolic capabilities of , while highlighting its potential as a chassis cell for synthetic biology, metabolic engineering, and protein expression. We discuss the bacterium's role in the production of chemicals, enzymes, and other industrial bioproducts, as well as its applications in medicine, such as combating infectious diseases and promoting gut health. In agriculture, has demonstrated potential as a biofertilizer, biocontrol agent, and stress tolerance enhancer for various crops. Despite its numerous promising applications, remains less studied than its Gram-negative counterpart, . This review emphasizes the need for further research and development of advanced engineering techniques and genetic editing technologies tailored for , ultimately unlocking its full potential in scientific and industrial contexts.
[细菌名称]，一种革兰氏阳性菌，已成为一种多功能微生物，在包括工业、医学和农业在内的各个领域都有重要应用。本综述旨在深入了解[细菌名称]的特征、遗传工具和代谢能力，同时突出其作为合成生物学、代谢工程和蛋白质表达底盘细胞的潜力。我们讨论了该细菌在化学品、酶和其他工业生物产品生产中的作用，以及其在医学上的应用，如对抗传染病和促进肠道健康。在农业方面，[细菌名称]已显示出作为各种作物的生物肥料、生物防治剂和抗逆增强剂的潜力。尽管有许多有前景的应用，但与革兰氏阴性菌[另一种细菌名称]相比，[细菌名称]的研究仍然较少。本综述强调需要进一步研究和开发针对[细菌名称]的先进工程技术和基因编辑技术，最终在科学和工业背景下充分发挥其潜力。
