Padhi Abhishek, Agarwal Ashwini, Saxena Shailendra K, Katoch C D S
Department of Microbiology, All India Institute of Medical Sciences, Rajkot, Gujarat 360110 India.
Centre for Advanced Research (CFAR), Faculty of Medicine, King George's Medical University (KGMU), Lucknow, India.
Virusdisease. 2023 Sep;34(3):345-355. doi: 10.1007/s13337-023-00841-y. Epub 2023 Sep 21.
In the rapidly evolving field of clinical virology, technological advancements have always played a pivotal role in driving transformative changes. This comprehensive review delves into the burgeoning integration of artificial intelligence (AI), machine learning, and deep learning into virological research and practice. As we elucidate, these computational tools have significantly enhanced diagnostic precision, therapeutic interventions, and epidemiological monitoring. Through in-depth analyses of notable case studies, we showcase how algorithms can optimize viral genome sequencing, accelerate drug discovery, and offer predictive insights into viral outbreaks. However, with these advancements come inherent challenges, particularly in data security, algorithmic biases, and ethical considerations. Addressing these challenges head-on, we discuss potential remedial measures and underscore the significance of interdisciplinary collaboration between virologists, data scientists, and ethicists. Conclusively, this review posits an outlook that anticipates a symbiotic relationship between AI-driven tools and virology, heralding a new era of proactive and personalized patient care.
在快速发展的临床病毒学领域,技术进步始终在推动变革性变化方面发挥着关键作用。这篇全面综述深入探讨了人工智能(AI)、机器学习和深度学习在病毒学研究与实践中的迅速融合。正如我们所阐明的,这些计算工具显著提高了诊断精度、治疗干预措施和流行病学监测水平。通过对显著案例研究的深入分析,我们展示了算法如何优化病毒基因组测序、加速药物发现,并对病毒爆发提供预测性见解。然而,随着这些进步也带来了一些固有挑战,特别是在数据安全、算法偏差和伦理考量方面。我们直面这些挑战,讨论了潜在的补救措施,并强调了病毒学家、数据科学家和伦理学家之间跨学科合作的重要性。总之,这篇综述提出了一种展望,预计人工智能驱动的工具与病毒学之间将形成共生关系,迎来主动和个性化患者护理的新时代。