Instituto de Medicina Integral Professor Fernando Figueira, Pós-graduação em Saúde Integral, Recife PE, Brazil.
Hospital Otávio de Freitas, Departamento de Reabilitação, Recife PE, Brazil.
Arq Neuropsiquiatr. 2023 Sep;81(9):816-824. doi: 10.1055/s-0043-1772832. Epub 2023 Oct 4.
Spinal muscular atrophy (SMA) is a rare genetic disease that causes progressive muscle weakness and impacts motor function. The type I is the most severe presentation and affects infants before 6 months old. In addition, the instruments available for assessing motor function have limitations when applied to infants with neuromuscular diseases and significant muscle weakness.
To translate, cross-culturally adapt, and validate the Children's Hospital of Philadelphia Infant Test of Neuromuscular Disorders (CHOP INTEND) to Brazilian Portuguese.
The present study comprised the translation, synthesis of translations, backtranslation, consolidation by a committee of experts, and test of the final version of the CHOP INTEND in 13 patients with SMA type I. We also assessed the content validity and reliability of the translated version.
The scale was translated considering semantic, structural, idiomatic, and cultural aspects. All agreement rates were > 0.8, the overall content validity index of the instrument was 0.98, and inter-rater reliability using the intraclass correlation coefficient was 0.998.
The Brazilian version of the CHOP INTEND met semantic and technical equivalence criteria with the original version and was valid and reliable for patients with SMA type I.
脊髓性肌萎缩症（SMA）是一种罕见的遗传性疾病，会导致进行性肌肉无力并影响运动功能。I 型是最严重的表现，会影响 6 个月以下的婴儿。此外，用于评估运动功能的仪器在应用于患有神经肌肉疾病和严重肌肉无力的婴儿时存在局限性。
将费城儿童医院婴儿神经肌肉疾病测试（CHOP INTEND）翻译成巴西葡萄牙语，并进行跨文化适应性验证。
本研究包括翻译、翻译合成、回译、专家委员会的整合以及对 13 名 I 型 SMA 患者的 CHOP INTEND 最终版本的测试。我们还评估了翻译版本的内容有效性和可靠性。
该量表在考虑语义、结构、习惯用法和文化方面进行了翻译。所有一致性率均>0.8，仪器的总体内容有效性指数为 0.98，使用组内相关系数的评分者间可靠性为 0.998。
CHOP INTEND 的巴西版本与原始版本在语义和技术等效性方面均符合标准，并且对 I 型 SMA 患者有效且可靠。
