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猪蛔虫肠道的细菌菌群与5-羟色胺的产生

The bacterial flora of the intestine of Ascaris suum and 5-hydroxytryptamine production.

作者信息

Hsu S C, Johansson K R, Donahue M J

出版信息

J Parasitol. 1986 Aug;72(4):545-9.

PMID:3783348
Abstract

Representative facultative anaerobes of the bacterial flora from the intestine of female Ascaris suum were isolated and identified. The number of bacteria in the intestine was approximately 4 X 10(9) per g wet weight of intestine. Seventeen of 19 of the isolated colonies were found to secrete 5-hydroxytryptamine in culture. Holding A. suum in an antibiotic-containing medium did not affect the levels of 5-hydroxytryptamine in the worm, which were 231 +/- 14 ng/g in antibiotic-media as compared to 250 +/- 16 ng/g in control media. This implied that the bacteria may not be contributing to the level of 5-hydroxytryptamine in the tissues of A. suum.

摘要

从雌性猪蛔虫肠道中分离并鉴定了具有代表性的兼性厌氧菌菌群。肠道中细菌数量约为每克肠道湿重4×10⁹个。在19个分离菌落中,有17个在培养过程中分泌5-羟色胺。将猪蛔虫置于含抗生素的培养基中并不影响虫体中5-羟色胺的水平,在抗生素培养基中为231±14 ng/g,而在对照培养基中为250±16 ng/g。这表明细菌可能对猪蛔虫组织中5-羟色胺的水平没有贡献。

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