Krook A, Fredlund H, Holmberg H
Eur J Clin Microbiol. 1986 Dec;5(6):639-42. doi: 10.1007/BF02013288.
A sandwich enzyme-linked immunosorbent assay was used for the detection of pneumococcal C polysaccharide in saliva samples from patients with radiologically verified pneumonia. In 16 of 29 patients (55%) with pneumococcal pneumonia, as verified by conventional culture methods, the antigen was present in saliva specimens. The test was negative in 35 of 36 patients (97%) with non-pneumococcal pneumonia and in all saliva samples from a control group, consisting of 25 patients with no signs of respiratory disease. It is concluded that the detection of pneumococcal C polysaccharide in saliva offers a valuable complement to conventional diagnostic methods for pneumococcal pneumonia.
采用夹心酶联免疫吸附测定法检测经放射学证实的肺炎患者唾液样本中的肺炎球菌C多糖。在29例经传统培养方法证实为肺炎球菌肺炎的患者中，有16例（55%）唾液标本中存在该抗原。36例非肺炎球菌肺炎患者中的35例（97%）以及由25例无呼吸道疾病体征的患者组成的对照组的所有唾液样本检测均为阴性。结论是，检测唾液中的肺炎球菌C多糖可为肺炎球菌肺炎的传统诊断方法提供有价值的补充。
