硒纳米粒子：绿色合成与生物医学应用。

Institute of Innovation Management, Kazan National Research Technological University, K. Marx Street 68, 420015 Kazan, Russia.

Molecules. 2023 Dec 15;28(24):8125. doi: 10.3390/molecules28248125.

Selenium nanoparticles (SeNPs) are extremely popular objects in nanotechnology. "Green" synthesis has special advantages due to the growing necessity for environmentally friendly, non-toxic, and low-cost methods. This review considers the biosynthesis mechanism of bacteria, fungi, algae, and plants, including the role of various biological substances in the processes of reducing selenium compounds to SeNPs and their further packaging. Modern information and approaches to the possible biomedical use of selenium nanoparticles are presented: antimicrobial, antiviral, anticancer, antioxidant, anti-inflammatory, and other properties, as well as the mechanisms of these processes, that have important potential therapeutic value.

硒纳米颗粒（SeNPs）是纳米技术中非常受欢迎的研究对象。由于对环境友好、无毒和低成本方法的需求不断增长，“绿色”合成具有特殊的优势。本综述考虑了细菌、真菌、藻类和植物的生物合成机制，包括各种生物物质在将硒化合物还原为 SeNPs 及其进一步包装过程中的作用。本文还介绍了现代信息和方法，探讨了硒纳米颗粒在可能的生物医学中的应用：抗菌、抗病毒、抗癌、抗氧化、抗炎等特性，以及这些过程的机制，这些都具有重要的潜在治疗价值。